1810. Noma (Cancrum oris): World Health Organisation's latest neglected tropical disease?

Ramat O Braimah, Azeez Butali, Peter Mossey, Wendy Thompson, Abdurrazaq Taiwo, Modupe Coker, Mujtaba Bala, Adebayo Ibikunle, Shafiu Abdullah, Abubakar Bello

Research output: Chapter in Book/Conference proceedingConference contributionpeer-review

Abstract

Background
Noma, also known as cancrum oris, necrotizing ulcerative stomatitis or gangrenous stomatitis, is a rapidly progressive and often fatal infection of the mouth and face. This disease predominantly affects children between the ages of 2 and 6 years old in poorly developed countries around the world where adequate nutrition, sanitation and cleanliness are lacking. Northwest Nigeria has a particularly high prevalence of the Noma.

Noma starts as gum disease and, without effective treatment (including antibiotics), around 90% die within two weeks and as such noma eminently fits the definition of a neglected tropical disease (NTD). The World Health Organization (WHO) has described 5-stages of the disease to include: Stage 1 (Acute Necrotizing Ulcerative Gingivitis), Stage 2 (Edematous), Stage 3 (Gangrenous), Stage 4 (Scarring) and Stage 5 (Late sequelae).
Original languageEnglish
Title of host publicationOpen Forum Infectious Diseases
PublisherInfectious Diseases Society of America
Volume10
EditionSuppl 2
DOIs
Publication statusPublished - 1 Dec 2023

Keywords

  • necrotizing ulcerative gingivitis
  • nigeria
  • noma
  • world health
  • tropical disease

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