25-hydroxyvitamin D deficiency is associated with increased aortic stiffness in patients with systemic lupus erythematosus

John A. Reynolds; Sahena Haque; Jacqueline L. Berry; Philip Pemberton; Lee Suan Teh; Pauline Ho; Rachel Gorodkin; Ian N. Bruce

doi:10.1093/rheumatology/ker352

25-hydroxyvitamin D deficiency is associated with increased aortic stiffness in patients with systemic lupus erythematosus

John A. Reynolds, Sahena Haque, Jacqueline L. Berry, Philip Pemberton, Lee Suan Teh, Pauline Ho, Rachel Gorodkin, Ian N. Bruce

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: To determine the relationship between serum vitamin D and markers of subclinical cardiovascular disease (CVD) in patients with SLE. Methods: We recruited SLE patients (≥4 ACR 1997 criteria) from outpatient clinics between January 2007 and January 2009. Vitamin D deficiency was defined as serum 25(OH)D 20 ng/ml. Subjects with SLEDAI-2K ≥4 had lower 25(OH)D than those with SLEDAI-2K

Original language	English
Article number	ker352
Pages (from-to)	544-551
Number of pages	7
Journal	Rheumatology
Volume	51
Issue number	3
DOIs	https://doi.org/10.1093/rheumatology/ker352
Publication status	Published - Mar 2012

Keywords

Cardiovascular risk
Disease activity
Systemic lupus erythematosus
Vascular stiffness
Vitamin D

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/rheumatology/ker352

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title = "25-hydroxyvitamin D deficiency is associated with increased aortic stiffness in patients with systemic lupus erythematosus",

abstract = "Objective: To determine the relationship between serum vitamin D and markers of subclinical cardiovascular disease (CVD) in patients with SLE. Methods: We recruited SLE patients (≥4 ACR 1997 criteria) from outpatient clinics between January 2007 and January 2009. Vitamin D deficiency was defined as serum 25(OH)D 20 ng/ml. Subjects with SLEDAI-2K ≥4 had lower 25(OH)D than those with SLEDAI-2K",

keywords = "Cardiovascular risk, Disease activity, Systemic lupus erythematosus, Vascular stiffness, Vitamin D",

author = "Reynolds, {John A.} and Sahena Haque and Berry, {Jacqueline L.} and Philip Pemberton and Teh, {Lee Suan} and Pauline Ho and Rachel Gorodkin and Bruce, {Ian N.}",

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T1 - 25-hydroxyvitamin D deficiency is associated with increased aortic stiffness in patients with systemic lupus erythematosus

AU - Reynolds, John A.

AU - Haque, Sahena

AU - Berry, Jacqueline L.

AU - Pemberton, Philip

AU - Teh, Lee Suan

AU - Ho, Pauline

AU - Gorodkin, Rachel

AU - Bruce, Ian N.

PY - 2012/3

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N2 - Objective: To determine the relationship between serum vitamin D and markers of subclinical cardiovascular disease (CVD) in patients with SLE. Methods: We recruited SLE patients (≥4 ACR 1997 criteria) from outpatient clinics between January 2007 and January 2009. Vitamin D deficiency was defined as serum 25(OH)D 20 ng/ml. Subjects with SLEDAI-2K ≥4 had lower 25(OH)D than those with SLEDAI-2K

AB - Objective: To determine the relationship between serum vitamin D and markers of subclinical cardiovascular disease (CVD) in patients with SLE. Methods: We recruited SLE patients (≥4 ACR 1997 criteria) from outpatient clinics between January 2007 and January 2009. Vitamin D deficiency was defined as serum 25(OH)D 20 ng/ml. Subjects with SLEDAI-2K ≥4 had lower 25(OH)D than those with SLEDAI-2K

KW - Cardiovascular risk

KW - Disease activity

KW - Systemic lupus erythematosus

KW - Vascular stiffness

KW - Vitamin D

U2 - 10.1093/rheumatology/ker352

DO - 10.1093/rheumatology/ker352

M3 - Article

C2 - 22120462

SN - 1462-0332

VL - 51

SP - 544

EP - 551

JO - Rheumatology

JF - Rheumatology

IS - 3

M1 - ker352

ER -

25-hydroxyvitamin D deficiency is associated with increased aortic stiffness in patients with systemic lupus erythematosus

Abstract

Keywords

UN SDGs

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