Abstract
We report on the synthesis of [2]rotaxanes driven by stabilization of the axle-forming transition state. A bifunctional macrocycle, with hydrogen bond donors at one end and acceptors at the other, is used to stabilize the charges that develop during the addition of a primary amine to a cyclic sulfate.
Original language | English |
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Journal | Journal of the American Chemical Society |
Early online date | 16 Jun 2017 |
DOIs | |
Publication status | Published - 2017 |