3D Skull Completion via Two-stage Conditional Diffusion-Based Signed Distance Fields

Zhenhong Liu, Xudong Ru, Xingce Wang*, Zhongke Wu, Yi Cheng Zhu, Chong Zhang, Alejandro F. Frangi

*Corresponding author for this work

Research output: Chapter in Book/Conference proceedingConference contributionpeer-review

Abstract

A fast and fully automatic design of 3D cranial implants is highly desired in cranioplasty, and is key to the treatment of skull trauma. We have defined the repair of skull defects as a 3D shape completion task by proposing a two-stage diffusion model based on the representation of 3D shapes using signed distance function (SDF). Specifically, we design a diffusion model conditioned on partial shapes, we compress the 3D shape into a compact latent representation using the encoder in the vector quantized variational autoencoder (VQ-VAE) and learn the diffusion model based on this compressed discrete representation. Encoding the latent space with the autoencoder can achieve high-quality 3D cranial shape completion. In order to accurately capture local and fine-grained shape details, the training data is geometrically encoded from a compactly learned code-book. The two-stage diffusion generator with a coarse-to-fine approach possesses precise and expressive structural modeling capabilities to ensure the supplementation of detailed geometric information. Experimental results verified sufficient expressiveness of our model with generating high-fidelity results with fine-grained local details, outperforming the state-of-the-art methods.

Original languageEnglish
Title of host publicationProceedings - 2024 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2024
EditorsMario Cannataro, Huiru Zheng, Lin Gao, Jianlin Cheng, Joao Luis de Miranda, Ester Zumpano, Xiaohua Hu, Young-Rae Cho, Taesung Park
PublisherIEEE
Pages2204-2209
Number of pages6
ISBN (Electronic)9798350386226
DOIs
Publication statusPublished - 2024
Event2024 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2024 - Lisbon, Portugal
Duration: 3 Dec 20246 Dec 2024

Publication series

NameProceedings - 2024 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2024

Conference

Conference2024 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2024
Country/TerritoryPortugal
CityLisbon
Period3/12/246/12/24

Keywords

  • 3D Shape Completion
  • Automatic Implant Generation
  • Diffusion model
  • Signed Distance Fields

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