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How to Design Phase I Trials in Oncology
Carter, L., O'Brien, C., Dean, E. & Cook, N., 17 Apr 2018, Methos and Biostatistics in Oncology: Understanding Clinical Research as an Applied Tool. Araujo, R. L. C. & Riechelmann, R. P. (eds.). Springer Nature, p. 165-187Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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How to design phase 1 trials in Oncology.
Carter, L., O'Brien, C., Dean, E. & Cook, N., 2018, Methods and Biostatistics in Oncology: Understanding Clinical Research as an Applied Tool,. p. 165-188Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Reply to K.K. Sahu et al
Cook, N. & Krzyzanowska, M. K., 1 Mar 2017, In: Journal of Oncology Practice. 13, 3, 1 p.Research output: Contribution to journal › Letter › peer-review
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124MO A single centre experience of patients with rare cancers referred for early phase clinical trials
Angelakas, A., Cook, N., Graham, D. M., Krebs, M., Thistlethwaite, F. & Carter, L., 22 Mar 2023, In: ESMO Open. 8, 1Research output: Contribution to journal › Meeting Abstract › peer-review
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The gut microbiome and its interaction with health, disease, treatment response and toxicity in patients advanced cancer: focus on lung cancer and immunotherapy
Tinsley, N. & Cook, N., 31 Dec 2020, In: Translational Lung Cancer Research. 9, 6, p. 2305-2307 3 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Enrolment of older adults with cancer in early phase clinical trials—an observational study on the experience in the north west of England
Gomes, F., Descamps, T., Lowe, J., Little, M., Lauste, R., Krebs, M., Graham, D., Thistlethwaite, F., Carter, L. & Cook, N., 9 Jun 2021, In: Age and Ageing. 50Research output: Contribution to journal › Article › peer-review
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Small cell carcinoma of the urinary bladder: a 15-year retrospective review of treatment and survival in the Anglian Cancer Network.
Mukesh, M., Cook, N., Hollingdale, A. E., Ainsworth, N. L. & Russell, S. G., Mar 2009, In: BJU international. 103, 6Research output: Contribution to journal › Article › peer-review
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Email communication practices and preferences among patients and providers in a large comprehensive cancer center
Cook, N., Dobriyal, A., Maganti, M., Sheinis, M., Wei, A.C.-C., Ringash, J. & Krzyzanowska, M. K., 2015, In: Journal of Clinical Oncology.Research output: Contribution to journal › Article › peer-review
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Challenge of the unknown: How can we improve clinical outcomes in cancer of unknown primary?
Conway, A. M., Mitchell, C. & Cook, N., 10 Aug 2019, In: Journal of Clinical Oncology. 37, 23, p. 2089-2090 2 p.Research output: Contribution to journal › Letter › peer-review
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Predictive in vivo animal models and translation to clinical trials.
Cook, N., Jodrell, D. I. & Tuveson, D. A., Mar 2012, In: Drug discovery today. 17, 5-6Research output: Contribution to journal › Article › peer-review
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Outcome of molecular profiling of sarcoma patients referred to an early phase clinical trial unit
Lowe, J., Nutman, C., Dransfield, J., Rothwell, D., Thistlethwaite, F., Cook, N., Graham, D., Brady, G., Wallace, A. J., Dive, C., Krebs, M. & Carter, L., 2020.Research output: Contribution to conference › Abstract › peer-review
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Novel Early Phase Clinical Trial Design in Oncology
O’Brien, C., Carter, L., Cook, N. & Dean, E., 1 Oct 2017, In: Pharmaceutical Medicine. 31, 5, p. 297-307 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile69 Downloads (Pure) -
1849P Ethnicity and socioeconomic deprivation in early phase clinical trials in a UK tertiary referral centre
Billy Graham Mariam, N., Rahman, R., Mistry, H., Aruketty, S., Adamson-Raieste, A., Church, M., Scott, J.-A., Carter, L., Thistlethwaite, F., Krebs, M., Cook, N. & Graham, D., 1 Sept 2021, In: Annals of Oncology. 32, p. S1247Research output: Contribution to journal › Meeting Abstract › peer-review
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Developing a CAncer genomics Digital Educational Tool to assess the knowledge and expectations of patients with advanced solid tumors (CADET)
Loong, H. H. F., Spreafico, A., Cook, N., Chan, K. K., Krishna, G. D., Chow, H., Yu, C., Kang, S., Blanchette, P. S., Bedard, P. L., Razak, A. R. A. & Siu, L. L., 2015, In: Journal of Clinical Oncology.Research output: Contribution to journal › Article › peer-review
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Antibiotic use and efficacy of small molecule inhibitors in patients with advanced cancer
Tan, G., Tinsley, N., Zhou, C., Villa, S., Lorigan, P., Blackhall, F., Krebs, M., Carter, L., Thistlethwaite, F., Hughes, A. & Cook, N., 8 Nov 2018, In: British Journal of Cancer. 119, 11, p. 25-25Research output: Contribution to journal › Meeting Abstract › peer-review
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Do Systemic Antibiotics Prior to Cancer Diagnosis Impact on All-Cause Mortality for Malignant Cancers? Findings from Two UK Population-Based Cohort Studies
Domzaridou, E., Van Staa, T. P., Renehan, A., Cook, N., Welfare, W., Ashcroft, D. M. & Palin, V., 24 Mar 2020, In: SSRN Electronic Journal.Research output: Contribution to journal › Article
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Assessing the role of the EGF receptor in the development and progression of pancreatic cancer
Cook, N., Frese, K. & Moore, M., 2 Apr 2014, In: Gastrointestinal Cancer: Targets and Therapy.Research output: Contribution to journal › Article › peer-review
Open AccessFile144 Downloads (Pure) -
Meeting Proceedings of the “Phase I: Where Science Becomes Medicine” Conference, Manchester, UK
Graham, D., Carter, L., Krebs, M., Jodrell, D. I., Armstrong, A., Kilgour, E., Illidge, T., Mowll-Clarke, J., Chown, R., Williams, K., Dive, C., Yorke, J., Dickinson, C., Hughes, A., Thistlethwaite, F., Bristow, R. & Cook, N., 2019, In: Journal of Immunotherapy and Precision Oncology. 2, 4, p. 156-174 19 p.Research output: Contribution to journal › Meeting Abstract › peer-review
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Integration of early supportive and palliative care in a patient’s journey with cancer
Lyon, J., Cook, N. & Lawrie, I., 3 Sept 2019, In: Progress in Palliative Care. 27, 5, p. 206-212 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile362 Downloads (Pure) -
A first-in-human phase 1 and pharmacological study of TAS-119, a novel selective Aurora A kinase inhibitor in patients with advanced solid tumours
Robbrecht, D. G. J., Lopez, J., Calvo, E., He, X., Hiroshi, H., Soni, N., Cook, N., Dowlati, A., Fasolo, A., Moreno, V., Eskens, F. A. L. M. & Bono, J. S. D., 19 Jan 2021, In: British Journal of Cancer.Research output: Contribution to journal › Article › peer-review
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Exome-Wide Association Study of Pancreatic Cancer Risk
Cook, N., 24 Feb 2018, In: Gastroenterology.Research output: Contribution to journal › Article › peer-review
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A Cancer Research UK phase I/IIa trial of BT1718 (a first in class Bicycle Drug Conjugate) given intravenously in patients with advanced solid tumours.
Banerji, U., Cook, N., Evans, T. R. J., Moreno Candilejo, I., Roxburgh, P., Kelly, C. L. S., Sabaratnam, N., Passi, R., Leslie, S., Katugampola, S., Godfrey, L., Tremayne, N., Bennett, G., Koehler, M., Langford, G., Symeonides, S. N. & Pittman, M., 20 May 2018, p. TPS2610-TPS2610.Research output: Contribution to conference › Abstract › peer-review
Open Access -
The International Core Literature Consensus (ICLC): an alternative curriculum for Oncologists.
Patel, S., Jagsi, R., Cook, N., Hughes-Davies, L. & Parkinson, C., Sept 2011, In: Journal of Cancer Education . 26, 3Research output: Contribution to journal › Article › peer-review
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EVALUATION OF OLDER PATIENTS IN EARLY PHASE CLINICAL TRIALS
Lowe, J., Lauste, R., Descamps, T., Krebs, M., Graham, D., Thistlethwaite, F., Carter, L. & Cook, N., Nov 2019, In: Journal of Geriatric Oncology. 10, 6, p. S109Research output: Contribution to journal › Meeting Abstract › peer-review
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384P Concordance of genomic alterations in tumour tissue and ctDNA in patients with colorectal cancer referred for early phase trials
Ramchander, N., Billy Graham Mariam, N., Rack, S., Shohdy, K., Franco, A., Thistlethwaite, F., Graham, D. M., Carter, L., Dransfield, S., Henshaw, A., Darlington, E., Rothwell, D., Burghel, G., Dive, C., Krebs, M. & Cook, N., 1 Sept 2022, In: Annals of Oncology. 33, p. S712Research output: Contribution to journal › Meeting Abstract › peer-review