A behavioral measure of the cochlear changes underlying temporary threshold shifts

Stella Howgate; Christopher J. Plack

doi:10.1016/j.heares.2011.03.009

A behavioral measure of the cochlear changes underlying temporary threshold shifts

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Abstract

It is well documented that exposure to recreational noise may result in a temporary threshold shift (TTS) due to cochlear dysfunction. A forward-masking paradigm was used to estimate the relative contribution of inner hair cell (IHC) and outer hair cell (OHC) dysfunction to TTS. Eighteen normal-hearing adults completed a test battery before, immediately after, and one week after attending a loud music venue. Personal dosimeters recorded mean equivalent exposure levels of 99.0 dB A. Shortly after exposure, there was an average TTS of 10.8 dB at 4 kHz, and an average reduction in the estimated gain provided by the OHCs of 11.5 dB. Gain reduction correlated significantly with TTS. The results suggest that OHC dysfunction can account almost entirely for the raised thresholds. For the test battery conducted a week after exposure, all measures showed recovery to pre-exposure values. © 2011 Elsevier B.V.

Original language	English
Pages (from-to)	78-87
Number of pages	9
Journal	Hearing Research
Volume	277
Issue number	1-2
DOIs	https://doi.org/10.1016/j.heares.2011.03.009
Publication status	Published - Jul 2011

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10.1016/j.heares.2011.03.009

Manchester Centre for Audiology and Deafness (ManCAD)
Munro, K. (PI), Millman, R. (PI), Lamb, W. (Support team), Dawes, P. (PI), Plack, C. (PI), Stone, M. (PI), Kluk-De Kort, K. (PI), Moore, D. (PI), Morton, C. (PI), Prendergast, G. (PI), Couth, S. (PI), Schlittenlacher, J. (PI), Chilton, H. (PI), Visram, A. (Researcher), Dillon, H. (PI), Guest, H. (Researcher), Heinrich, A. (PI), Jackson, I. (Researcher), Littlejohn, J. (Researcher), Jones, L. (PI), Lough, M. (Researcher), Morgan, R. (Researcher), Perugia, E. (Researcher), Roughley, A. (Researcher), Whiston, H. (Researcher), Wright, C. (Support team), Saunders, G. (PI), Kelly, C. (PI), Cross, H. (Researcher), Loughran, M. (Researcher) & Hoseinabadi, R. (PI)
Project: Research

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title = "A behavioral measure of the cochlear changes underlying temporary threshold shifts",

abstract = "It is well documented that exposure to recreational noise may result in a temporary threshold shift (TTS) due to cochlear dysfunction. A forward-masking paradigm was used to estimate the relative contribution of inner hair cell (IHC) and outer hair cell (OHC) dysfunction to TTS. Eighteen normal-hearing adults completed a test battery before, immediately after, and one week after attending a loud music venue. Personal dosimeters recorded mean equivalent exposure levels of 99.0 dB A. Shortly after exposure, there was an average TTS of 10.8 dB at 4 kHz, and an average reduction in the estimated gain provided by the OHCs of 11.5 dB. Gain reduction correlated significantly with TTS. The results suggest that OHC dysfunction can account almost entirely for the raised thresholds. For the test battery conducted a week after exposure, all measures showed recovery to pre-exposure values. {\textcopyright} 2011 Elsevier B.V.",

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year = "2011",

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AU - Howgate, Stella

AU - Plack, Christopher J.

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N2 - It is well documented that exposure to recreational noise may result in a temporary threshold shift (TTS) due to cochlear dysfunction. A forward-masking paradigm was used to estimate the relative contribution of inner hair cell (IHC) and outer hair cell (OHC) dysfunction to TTS. Eighteen normal-hearing adults completed a test battery before, immediately after, and one week after attending a loud music venue. Personal dosimeters recorded mean equivalent exposure levels of 99.0 dB A. Shortly after exposure, there was an average TTS of 10.8 dB at 4 kHz, and an average reduction in the estimated gain provided by the OHCs of 11.5 dB. Gain reduction correlated significantly with TTS. The results suggest that OHC dysfunction can account almost entirely for the raised thresholds. For the test battery conducted a week after exposure, all measures showed recovery to pre-exposure values. © 2011 Elsevier B.V.

AB - It is well documented that exposure to recreational noise may result in a temporary threshold shift (TTS) due to cochlear dysfunction. A forward-masking paradigm was used to estimate the relative contribution of inner hair cell (IHC) and outer hair cell (OHC) dysfunction to TTS. Eighteen normal-hearing adults completed a test battery before, immediately after, and one week after attending a loud music venue. Personal dosimeters recorded mean equivalent exposure levels of 99.0 dB A. Shortly after exposure, there was an average TTS of 10.8 dB at 4 kHz, and an average reduction in the estimated gain provided by the OHCs of 11.5 dB. Gain reduction correlated significantly with TTS. The results suggest that OHC dysfunction can account almost entirely for the raised thresholds. For the test battery conducted a week after exposure, all measures showed recovery to pre-exposure values. © 2011 Elsevier B.V.

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DO - 10.1016/j.heares.2011.03.009

M3 - Article

SN - 1878-5891

VL - 277

SP - 78

EP - 87

JO - Hearing Research

JF - Hearing Research

IS - 1-2

ER -

A behavioral measure of the cochlear changes underlying temporary threshold shifts

Abstract

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Manchester Centre for Audiology and Deafness (ManCAD)

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