A biomimetic ferric hydroperoxo porphyrin intermediate

Sam P. De Visser, Joan Selverstone Valentine, Wonwoo Nam

    Research output: Contribution to journalArticlepeer-review


    "Chemical Equation Presented" OOH, my! The protonation of a side-on high-spin ferric peroxo species yields the corresponding end-on low-spin ferric hydroperoxo intermediate (see picture), which is a precursor of Compound I and has been frequently proposed as a reactive species in heme enzymes. This ferric hydroperoxo complex can be used to study reactivities of similar species in substrate oxygenation and hydroperoxide O-O bond cleavage reactions. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.
    Original languageEnglish
    Pages (from-to)2099-2101
    Number of pages2
    JournalAngewandte Chemie - International Edition
    Issue number12
    Publication statusPublished - 15 Mar 2010


    • Bioinorganic chemistry
    • Ferric hydroperoxo complexes
    • Heme proteins
    • Oxygen activation
    • Porphyrinoids


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