A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites

Shaowei Zhang, Michiyo Sakuma, Girdhar S. Deora, Colin Levy, Alex Klausing, Carlo Breda, Kevin D. Read, Benjamin P. Ross, Marina Wright Muelas, Philip Day, Stephen O'Hagan, Douglas Kell, Robert Schwarcz, David Leys, Derren Heyes, Flaviano Giorgini, Nigel Scrutton

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Neuroscience

Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science