A comparison of narrow band phototherapy (TL-01) and photochemotherapy (PUVA) in the management of polymorphic light eruption

D. Bilsland, S. A. George, N. K. Gibbs, T. Aitchison, B. E. Johnson, J. Ferguson

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Twenty-five patients suffering from severe polymorphic light eruption (PLE) were randomized to either photochemotherapy (PUVA) or narrow-band phototherapy (TL-01 UVB) treatment in early spring; patients receiving UVB were given placebo tablets to achieve a matching therapy procedure. During the 4 months following treatment, patient exposure to solar UVB was monitored with polysulphone badges. PLE occurrence, severity, and restriction of outdoor activity were recorded, using weekly diary-sheets. Analysis of covariance on this data, using the logarithm of UVB exposure as the explanatory variable, showed no significant differences between the treatments. TL-01 UVB is an effective alternative to PUVA in the management of PLE.
    Original languageEnglish
    Pages (from-to)708-712
    Number of pages4
    JournalBritish Journal of Dermatology
    Volume129
    Issue number6
    DOIs
    Publication statusPublished - 1993

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