A conformational sampling model for radical catalysis in pyridoxal phosphate- and cobalamin-dependent enzymes

BJ Menon; K Fisher; S Rigby; NS Scrutton; David Leys

doi:10.1074/jbc.M114.590471

A conformational sampling model for radical catalysis in pyridoxal phosphate- and cobalamin-dependent enzymes

BJ Menon, K Fisher, S Rigby, NS Scrutton, David Leys

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	34161-34174
Number of pages	13
Journal	Journal of Biological Chemistry
Volume	289
Issue number	49
DOIs	https://doi.org/10.1074/jbc.M114.590471
Publication status	Published - 2014

Keywords

Adenosylcobalamin (AdoCbl)
Conformational Sampling
Domain Dynamics
Electron Paramagnetic Resonance (EPR)
Ornithine Aminomutase
Protein Dynamic
Pyridoxal Phosphate
Radical

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10.1074/jbc.M114.590471Licence: CC BY

Biological Mass Spectrometry (BioMS) Facility
Knight, D. (Platform Lead), Warwood, S. (Senior Technical Specialist), Selley, J. (Technical Specialist), Taylor, G. (Technical Specialist), Fullwood, P. (Technical Specialist), Keevill, E.-J. (Senior Technician) & Allsey, J. (Technician)
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Cite this

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title = "A conformational sampling model for radical catalysis in pyridoxal phosphate- and cobalamin-dependent enzymes",

keywords = "Adenosylcobalamin (AdoCbl), Conformational Sampling, Domain Dynamics, Electron Paramagnetic Resonance (EPR), Ornithine Aminomutase, Protein Dynamic, Pyridoxal Phosphate, Radical",

author = "BJ Menon and K Fisher and S Rigby and NS Scrutton and David Leys",

year = "2014",

doi = "10.1074/jbc.M114.590471",

language = "English",

volume = "289",

pages = "34161--34174",

journal = "Journal of Biological Chemistry",

issn = "0021-9258",

publisher = "American Society for Biochemistry and Molecular Biology Inc.",

number = "49",

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TY - JOUR

T1 - A conformational sampling model for radical catalysis in pyridoxal phosphate- and cobalamin-dependent enzymes

AU - Menon, BJ

AU - Fisher, K

AU - Rigby, S

AU - Scrutton, NS

AU - Leys, David

PY - 2014

Y1 - 2014

KW - Adenosylcobalamin (AdoCbl)

KW - Conformational Sampling

KW - Domain Dynamics

KW - Electron Paramagnetic Resonance (EPR)

KW - Ornithine Aminomutase

KW - Protein Dynamic

KW - Pyridoxal Phosphate

KW - Radical

U2 - 10.1074/jbc.M114.590471

DO - 10.1074/jbc.M114.590471

M3 - Article

C2 - 25213862

SN - 0021-9258

VL - 289

SP - 34161

EP - 34174

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

IS - 49

ER -

A conformational sampling model for radical catalysis in pyridoxal phosphate- and cobalamin-dependent enzymes

Keywords

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Equipment

Biological Mass Spectrometry (BioMS) Facility

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