A de novo Self‐Assembling Peptide Hydrogel Biosensor with Covalently Immobilised DNA‐Recognising Motifs

Patrick King; Alberto Saiani; Elena Bichenkova; Aline Saiani

doi:10.1039/C6CC01433J

A de novo Self‐Assembling Peptide Hydrogel Biosensor with Covalently Immobilised DNA‐Recognising Motifs

Patrick King, Alberto Saiani, Elena Bichenkova, Aline Saiani

Research output: Contribution to journal › Article › peer-review

Abstract

We report here the first experimental evidence of a self-assembling three-dimensional (3D) peptide hydrogel, with recognition motifs immobilized on the surface of fibres capable of sequence-specific oligonucleotide detection. These systems have the potential to be further developed into diagnostic and prognostic tools in human pathophysiology.

Original language	English
Pages (from-to)	6697-6700
Number of pages	4
Journal	Chemical Communications
Volume	52
Issue number	40
Early online date	19 Apr 2016
DOIs	https://doi.org/10.1039/C6CC01433J
Publication status	Published - 18 May 2016

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title = "A de novo Self‐Assembling Peptide Hydrogel Biosensor with Covalently Immobilised DNA‐Recognising Motifs",

abstract = "We report here the first experimental evidence of a self-assembling three-dimensional (3D) peptide hydrogel, with recognition motifs immobilized on the surface of fibres capable of sequence-specific oligonucleotide detection. These systems have the potential to be further developed into diagnostic and prognostic tools in human pathophysiology.",

author = "Patrick King and Alberto Saiani and Elena Bichenkova and Aline Saiani",

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AU - Bichenkova, Elena

AU - Saiani, Aline

PY - 2016/5/18

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N2 - We report here the first experimental evidence of a self-assembling three-dimensional (3D) peptide hydrogel, with recognition motifs immobilized on the surface of fibres capable of sequence-specific oligonucleotide detection. These systems have the potential to be further developed into diagnostic and prognostic tools in human pathophysiology.

AB - We report here the first experimental evidence of a self-assembling three-dimensional (3D) peptide hydrogel, with recognition motifs immobilized on the surface of fibres capable of sequence-specific oligonucleotide detection. These systems have the potential to be further developed into diagnostic and prognostic tools in human pathophysiology.

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DO - 10.1039/C6CC01433J

M3 - Article

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EP - 6700

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 40

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A de novo Self‐Assembling Peptide Hydrogel Biosensor with Covalently Immobilised DNA‐Recognising Motifs

Abstract

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