Abstract
(Chemical Equation Presented) Thionium ions, generated by the addition of thiols to N-benzylglyoxamides, undergo a dearomatizing spirocyclization. The alkyl or arylsulfanyl group introduced during the thionium ion cyclization can act as a synthetic handle and a stereochemical control element during modifications of the azaspirocyclic frameworks (RF = CH 2CH2C8F17). © 2008 American Chemical Society.
| Original language | English |
|---|---|
| Pages (from-to) | 1441-1444 |
| Number of pages | 3 |
| Journal | Organic Letters |
| Volume | 10 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 3 Apr 2008 |
Keywords
- PUMMERER REACTION CHEMISTRY
- CYCLATIVE-CAPTURE STRATEGY
- NITROGEN-HETEROCYCLES
- N-HETEROCYCLES
- ALKALOIDS
- LACTAMS
- OXINDOLES
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CCDC 669888: Experimental Crystal Structure Determination
Ovens, C. (Contributor), Martin, N. (Contributor) & Procter, D. (Contributor), Cambridge Crystallographic Data Centre, 4 Dec 2007
DOI: 10.5517/ccqh29k, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccqh29k&sid=DataCite
Dataset
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CCDC 669889: Experimental Crystal Structure Determination
Ovens, C. (Contributor), Martin, N. (Contributor) & Procter, D. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2009
DOI: 10.5517/ccqh2bl, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccqh2bl&sid=DataCite
Dataset