A Delphi consensus study on salvage brachytherapy for prostate cancer relapse after radiotherapy, a Uro-GEC study

Emmie Kaljouw, Bradley R Pieters, György Kovács, Peter J Hoskin

Research output: Contribution to journalArticlepeer-review


BACKGROUND AND PURPOSE: Patients treated with low radiotherapy dose or treated at young age are at a risk of developing local relapse. Although data are preliminary, brachytherapy seems an attractive treatment option for recurrent prostate cancer after previous radiotherapy. Therefore, the UroGEC group of the GEC-ESTRO conducted a Delphi study, to explore expert opinion on the management of salvage prostate brachytherapy.

MATERIAL AND METHODS: For this study, a series of digital questionnaires were sent, which enabled data collection from an international group of experienced participants. Consensus was defined as 80% agreement for each question.

RESULTS: Eighteen experts completed all rounds of the Delphi study. After the final round consensus was reached on 17 out of 38 (45%) questions. Consensus was reached in 52% of questions about patient selection, in 50% of the questions about diagnostic tests and in 22% of the questions on performing salvage prostate brachytherapy.

CONCLUSIONS: The group was able to find consensus on less than half of the questions. Most consensus was reached on topics involving patient selection and diagnostic tests, where participants could build on their experience of daily practice. However, the way to perform the salvage treatment is less established and results in more disagreement between participants.

Original languageEnglish
Pages (from-to)122-30
Number of pages9
JournalRadiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Issue number1
Publication statusPublished - Jan 2016


  • Aged
  • Aged, 80 and over
  • Brachytherapy/methods
  • Consensus
  • Delphi Technique
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local/diagnosis
  • Patient Selection
  • Prostate-Specific Antigen/blood
  • Prostatic Neoplasms/diagnosis
  • Radiotherapy Dosage
  • Salvage Therapy/methods

Research Beacons, Institutes and Platforms

  • Manchester Cancer Research Centre


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