Abstract
Chamical Equation Presentation Waiting in line: Aldehyde groups take turns reacting in a Sml2-mediated cyclization cascade to form the skeleton 2 of the antibacterial natural product pleuro-mutilin. Two rings and four contiguous stereocenters are constructed during the cascade with complete diastereocontrol. © 2009 Wiley-VCH Verlag GmbH & Co. KCaA.
Original language | English |
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Pages (from-to) | 9315-9317 |
Number of pages | 2 |
Journal | Angewandte Chemie - International Edition |
Volume | 48 |
Issue number | 49 |
DOIs | |
Publication status | Published - 23 Nov 2009 |
Keywords
- Natural products
- Radical reactions
- Samarium
- Total synthesis
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CCDC 747912: Experimental Crystal Structure Determination
Helm, M. D. (Contributor), Da Silva, M. (Contributor), Sucunza, D. (Contributor), Findley, T. J. K. (Contributor) & Procter, D. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2010
DOI: 10.5517/cct386c, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cct386c&sid=DataCite
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