A facile method for the stain-free visualization of hierarchical structures with electron microscopy

Paul E.  Williams; Eric A.  Appel; Samuel T. Jones; Jesus del Barrio; Yang Lan; Oren A.  Scherman

doi:10.1002/pola.27517

A facile method for the stain-free visualization of hierarchical structures with electron microscopy

Paul E. Williams, Eric A. Appel, Samuel T. Jones, Jesus del Barrio, Yang Lan, Oren A. Scherman

Materials Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

Diblock copolymers form hierarchical morphologies with numerous applications in drug delivery and as nanoreactors. Yet, the visualization of these structures by electron microscopy can be extremely difficult, requiring complex staining techniques with associated health risks and the potential to alter structural morphology. Reported here is the synthesis of diblock copolymers by RAFT containing 3,5‐bis(trifluoromethyl)phenyl functionality allowing for facile visualization of their resulting hierarchical structures by TEM with no further sample preparation.

Original language	English
Pages (from-to)	842-845
Number of pages	4
Journal	Journal of Polymer Science Part A: Polymer Chemistry
Volume	53
Issue number	7
DOIs	https://doi.org/10.1002/pola.27517
Publication status	Published - 19 Feb 2015

Access to Document

10.1002/pola.27517

Cite this

@article{5159b979b5cb42f095d83fca5ebaf9f8,

title = "A facile method for the stain-free visualization of hierarchical structures with electron microscopy",

abstract = "Diblock copolymers form hierarchical morphologies with numerous applications in drug delivery and as nanoreactors. Yet, the visualization of these structures by electron microscopy can be extremely difficult, requiring complex staining techniques with associated health risks and the potential to alter structural morphology. Reported here is the synthesis of diblock copolymers by RAFT containing 3,5‐bis(trifluoromethyl)phenyl functionality allowing for facile visualization of their resulting hierarchical structures by TEM with no further sample preparation.",

author = "Williams, {Paul E.} and Appel, {Eric A.} and Jones, {Samuel T.} and Barrio, {Jesus del} and Yang Lan and Scherman, {Oren A.}",

year = "2015",

month = feb,

day = "19",

doi = "10.1002/pola.27517",

language = "English",

volume = "53",

pages = "842--845",

journal = "Journal of Polymer Science Part A: Polymer Chemistry",

issn = "1099-0518",

publisher = "John Wiley & Sons Ltd",

number = "7",

}

TY - JOUR

T1 - A facile method for the stain-free visualization of hierarchical structures with electron microscopy

AU - Williams, Paul E.

AU - Appel, Eric A.

AU - Jones, Samuel T.

AU - Barrio, Jesus del

AU - Lan, Yang

AU - Scherman, Oren A.

PY - 2015/2/19

Y1 - 2015/2/19

N2 - Diblock copolymers form hierarchical morphologies with numerous applications in drug delivery and as nanoreactors. Yet, the visualization of these structures by electron microscopy can be extremely difficult, requiring complex staining techniques with associated health risks and the potential to alter structural morphology. Reported here is the synthesis of diblock copolymers by RAFT containing 3,5‐bis(trifluoromethyl)phenyl functionality allowing for facile visualization of their resulting hierarchical structures by TEM with no further sample preparation.

AB - Diblock copolymers form hierarchical morphologies with numerous applications in drug delivery and as nanoreactors. Yet, the visualization of these structures by electron microscopy can be extremely difficult, requiring complex staining techniques with associated health risks and the potential to alter structural morphology. Reported here is the synthesis of diblock copolymers by RAFT containing 3,5‐bis(trifluoromethyl)phenyl functionality allowing for facile visualization of their resulting hierarchical structures by TEM with no further sample preparation.

UR - http://dx.doi.org/10.1002/pola.27517

U2 - 10.1002/pola.27517

DO - 10.1002/pola.27517

M3 - Article

SN - 1099-0518

VL - 53

SP - 842

EP - 845

JO - Journal of Polymer Science Part A: Polymer Chemistry

JF - Journal of Polymer Science Part A: Polymer Chemistry

IS - 7

ER -

A facile method for the stain-free visualization of hierarchical structures with electron microscopy

Abstract

Access to Document

Other files and links

Fingerprint

Cite this