A laser desorption/resonance enhanced photoionisation TOF-system for the spatially resolved trace analysis of elements

J. Maul, T. Berg, K. Eberhardt, I. Hoog, G. Huber, S. Karpuk, G. Passler, N. Trautmann, Ilya Strashnov, K Wendt

    Research output: Contribution to journalArticlepeer-review

    Abstract

    A novel method for direct and spatially resolved elemental trace analysis with high sensitivity and elemental selectivity is presented. The concept is based on the combination of a commercial MALDI-TOF mass spectrometer with a pulsed laser system for resonant postionisation of neutrals. While the MALDI method is usually applied for investigations of large organic compounds and biomolecules, the technique discussed here concerns the low mass range around 1 ⩽ A ⩽ 300. The analytical performances of the setup with respect to mass analysis, spatial resolution and overall detection efficiency are discussed.
    Original languageEnglish
    Pages (from-to)644-650
    Number of pages7
    JournalNuclear Instruments and Methods in Physics Research B Beam Interactions with Materials and Atoms
    Volume226
    Issue number4
    DOIs
    Publication statusPublished - Dec 2004

    Keywords

    • laser desorption
    • MALDI-TOF
    • resonance ionisation
    • elemental trace analysis

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