A Love plate biosensor utilizing a polymer layer

Electra Gizeli, Nicholas J Goddard, Christopher Lowe, Adrian C Stevenson

    Research output: Contribution to journalArticlepeer-review

    Abstract

    A Love plate device, based on an SSBW piezoelec. substrate coated with a polymer (PMMA) layer, was used to excite a surface guiding shear horizontal wave. The surface mass sensitivity of the device was calcd. as a function of the thickness of the polymer layer, using a modeling theory derived for the polymer-Love plate. LB films were used to assess exptl. the surface mass sensitivity and results were compared with theor. predictions. Investigation of protein interaction with the PMMA surface was performed by following the adsorption of IgG in the range 1-400 micro g/mL. Finally, the deposition of a protein multilayer, consisted of IgG/anti-IgG and protein A, was clearly detected using the polymer-coated Love plate device. [on SciFinder (R)]
    Original languageEnglish
    Pages (from-to)131-7
    JournalSens. Actuators, B
    VolumeB6
    Issue number1-3
    Publication statusPublished - 1992

    Keywords

    • Biosensors (Love plate, using polymer layer)
    • Proteins Role: PRP (Properties) (adsorption and detection of, to polymer layer of Love plate biosensor)
    • Love plate biosensor polymethylmethacrylate
    • protein interaction polymer Love plate biosensor

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