Abstract
A modular approach to the synthesis of sensors is described. In this approach a central dye scaffold, prepared from the SNAr reaction between a halo-substituted azo-dye and a disubstituted phenol, was decorated with a representative carbohydrate or macrocycle using Sharpless click chemistry. Regiochemical issues in the click reaction are also addressed.
Original language | English |
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Journal | SYNLETT |
DOIs | |
Publication status | Published - 23 Dec 2015 |
Keywords
- azo-dye - recognition - click - macromolecule - crown ethers - cycloaddition - regiocontrol - aziridine - scaffold - sensors