A multicentre study investigating subcutaneous etonogestrel implants with injectable testosterone decanoate as a potential long-acting male contraceptive

Brian M. Brady; J. K. Amory; A. Perheentupa; M. Zitzmann; C. J. Hay; D. Apter; R. A. Anderson; W. J. Bremner; P. Pollanen; E. Nieschlag; F. C W Wu; W. M. Kersemaekers

doi:10.1093/humrep/dei300

A multicentre study investigating subcutaneous etonogestrel implants with injectable testosterone decanoate as a potential long-acting male contraceptive

Brian M. Brady, J. K. Amory, A. Perheentupa, M. Zitzmann, C. J. Hay, D. Apter, R. A. Anderson, W. J. Bremner, P. Pollanen, E. Nieschlag, F. C W Wu, W. M. Kersemaekers

Research output: Contribution to journal › Article › peer-review

Abstract

Background: The combination of etonogestrel implants with injectable testosterone decanoate was investigated as a potential male contraceptive. Methods: One hundred and thirty subjects were randomly assigned to three treatment groups, all receiving two etonogestrel rods (204 mg etonogestrel) and 400 mg testosterone decanoate either every 4 weeks (group I, n = 42), or every 6 weeks (group II, n = 51) or 600 mg testosterone decanoate every 6 weeks (group III, n = 37) for a treatment period of 48 weeks. Results: One hundred and ten men completed 48 weeks of treatment. Sperm concentrations of

Original language	English
Pages (from-to)	285-294
Number of pages	9
Journal	Human Reproduction
Volume	21
Issue number	1
DOIs	https://doi.org/10.1093/humrep/dei300
Publication status	Published - Jan 2006

Keywords

Etonogestrel
Gestogen
Male contraceptive
Spermatogenesis
Testosterone decanoate

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Brady, B. M., Amory, J. K., Perheentupa, A., Zitzmann, M., Hay, C. J., Apter, D., Anderson, R. A., Bremner, W. J., Pollanen, P., Nieschlag, E., Wu, F. C. W., & Kersemaekers, W. M. (2006). A multicentre study investigating subcutaneous etonogestrel implants with injectable testosterone decanoate as a potential long-acting male contraceptive. Human Reproduction, 21(1), 285-294. https://doi.org/10.1093/humrep/dei300

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title = "A multicentre study investigating subcutaneous etonogestrel implants with injectable testosterone decanoate as a potential long-acting male contraceptive",

abstract = "Background: The combination of etonogestrel implants with injectable testosterone decanoate was investigated as a potential male contraceptive. Methods: One hundred and thirty subjects were randomly assigned to three treatment groups, all receiving two etonogestrel rods (204 mg etonogestrel) and 400 mg testosterone decanoate either every 4 weeks (group I, n = 42), or every 6 weeks (group II, n = 51) or 600 mg testosterone decanoate every 6 weeks (group III, n = 37) for a treatment period of 48 weeks. Results: One hundred and ten men completed 48 weeks of treatment. Sperm concentrations of",

keywords = "Etonogestrel, Gestogen, Male contraceptive, Spermatogenesis, Testosterone decanoate",

author = "Brady, {Brian M.} and Amory, {J. K.} and A. Perheentupa and M. Zitzmann and Hay, {C. J.} and D. Apter and Anderson, {R. A.} and Bremner, {W. J.} and P. Pollanen and E. Nieschlag and Wu, {F. C W} and Kersemaekers, {W. M.}",

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year = "2006",

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doi = "10.1093/humrep/dei300",

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Brady, BM, Amory, JK, Perheentupa, A, Zitzmann, M, Hay, CJ, Apter, D, Anderson, RA, Bremner, WJ, Pollanen, P, Nieschlag, E, Wu, FCW & Kersemaekers, WM 2006, 'A multicentre study investigating subcutaneous etonogestrel implants with injectable testosterone decanoate as a potential long-acting male contraceptive', Human Reproduction, vol. 21, no. 1, pp. 285-294. https://doi.org/10.1093/humrep/dei300

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AU - Brady, Brian M.

AU - Amory, J. K.

AU - Perheentupa, A.

AU - Zitzmann, M.

AU - Hay, C. J.

AU - Apter, D.

AU - Anderson, R. A.

AU - Bremner, W. J.

AU - Pollanen, P.

AU - Nieschlag, E.

AU - Wu, F. C W

AU - Kersemaekers, W. M.

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AB - Background: The combination of etonogestrel implants with injectable testosterone decanoate was investigated as a potential male contraceptive. Methods: One hundred and thirty subjects were randomly assigned to three treatment groups, all receiving two etonogestrel rods (204 mg etonogestrel) and 400 mg testosterone decanoate either every 4 weeks (group I, n = 42), or every 6 weeks (group II, n = 51) or 600 mg testosterone decanoate every 6 weeks (group III, n = 37) for a treatment period of 48 weeks. Results: One hundred and ten men completed 48 weeks of treatment. Sperm concentrations of

KW - Etonogestrel

KW - Gestogen

KW - Male contraceptive

KW - Spermatogenesis

KW - Testosterone decanoate

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DO - 10.1093/humrep/dei300

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JF - Human Reproduction

IS - 1

ER -

A multicentre study investigating subcutaneous etonogestrel implants with injectable testosterone decanoate as a potential long-acting male contraceptive

Abstract

Keywords

UN SDGs

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