Abstract
| Original language | English |
|---|---|
| Journal | Molecular psychiatry |
| DOIs | |
| Publication status | Published - 17 Mar 2015 |
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- Dementia@Manchester
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In: Molecular psychiatry, 17.03.2015.
Research output: Contribution to journal › Article › peer-review
TY - JOUR
T1 - A novel Alzheimer disease locus located near the gene encoding tau protein.
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A2 - Craig, David
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A2 - Rubinsztein, David C
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N1 - P30 AG013846, NIA NIH HHS, United StatesR01 AG017917, NIA NIH HHS, United StatesU01 AG016976, NIA NIH HHS, United StatesU01 AG032984, NIA NIH HHS, United States
PY - 2015/3/17
Y1 - 2015/3/17
N2 - APOE ɛ4, the most significant genetic risk factor for Alzheimer disease (AD), may mask effects of other loci. We re-analyzed genome-wide association study (GWAS) data from the International Genomics of Alzheimer's Project (IGAP) Consortium in APOE ɛ4+ (10 352 cases and 9207 controls) and APOE ɛ4- (7184 cases and 26 968 controls) subgroups as well as in the total sample testing for interaction between a single-nucleotide polymorphism (SNP) and APOE ɛ4 status. Suggestive associations (P
AB - APOE ɛ4, the most significant genetic risk factor for Alzheimer disease (AD), may mask effects of other loci. We re-analyzed genome-wide association study (GWAS) data from the International Genomics of Alzheimer's Project (IGAP) Consortium in APOE ɛ4+ (10 352 cases and 9207 controls) and APOE ɛ4- (7184 cases and 26 968 controls) subgroups as well as in the total sample testing for interaction between a single-nucleotide polymorphism (SNP) and APOE ɛ4 status. Suggestive associations (P
U2 - 10.1038/mp.2015.23
DO - 10.1038/mp.2015.23
M3 - Article
C2 - 25778476
SN - 1359-4184
JO - Molecular psychiatry
JF - Molecular psychiatry
ER -