Abstract
The naturally occurring 3-oxohexanoyl-L-homoserinelactone (1a), a bacterial autoinducer has been prepared in 47% overall yield by condensing stable 3-oxohexanoic acid (2), prepared by hydrolysis from the corresponding ester (3), with L-homoserinelactone using hydroxybenzotriazole (HOBT) and dicyclohexylcarbodiimide (DCC) in non-aqueous media.
Original language | English |
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Pages (from-to) | 1883-1884 |
Number of pages | 1 |
Journal | Tetrahedron Letters |
Volume | 37 |
Issue number | 11 |
DOIs | |
Publication status | Published - 11 Mar 1996 |