A novel PCR-RFLP assay for the detection of a polymorphism in the 3′ of STAT6 gene

M. Amoli; W. E R Ollier; A. H. Hajeer

A novel PCR-RFLP assay for the detection of a polymorphism in the 3′ of STAT6 gene

M. Amoli, W. E R Ollier, A. H. Hajeer

Research output: Contribution to journal › Article › peer-review

Abstract

We have identified a novel single nucleotide polymorphism at position 2964 (G/A) in the 3′ untranslated region of the human STAT6 gene (GeneBank Accession No. U16031). A novel PCR-RFLP method has been devised for this polymorphism using the amplification-created restriction site (ACRS) method. Allele frequencies in the UK Caucasian population were found to be 0.33 for allele A and 0.67 for allele G.

Original language	English
Pages (from-to)	349-350
Number of pages	1
Journal	Genes and Immunity
Volume	1
Issue number	5
Publication status	Published - Jun 2000

Keywords

Biallelic
PCR-RFLP
Polymorphism
STAT6

Cite this

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title = "A novel PCR-RFLP assay for the detection of a polymorphism in the 3′ of STAT6 gene",

abstract = "We have identified a novel single nucleotide polymorphism at position 2964 (G/A) in the 3′ untranslated region of the human STAT6 gene (GeneBank Accession No. U16031). A novel PCR-RFLP method has been devised for this polymorphism using the amplification-created restriction site (ACRS) method. Allele frequencies in the UK Caucasian population were found to be 0.33 for allele A and 0.67 for allele G.",

keywords = "Biallelic, PCR-RFLP, Polymorphism, STAT6",

author = "M. Amoli and Ollier, \{W. E R\} and Hajeer, \{A. H.\}",

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year = "2000",

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AU - Ollier, W. E R

AU - Hajeer, A. H.

N1 - UI - 21040289 LA - eng RN - 0 (3' Untranslated Regions) RN - 0 (DNA Primers) RN - 0 (Trans-Activators) RN - 168115-60-4 (Stat6 protein) PT - Journal Article DA - 20010124 IS - 1466-4879 SB - IM CY - England

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N2 - We have identified a novel single nucleotide polymorphism at position 2964 (G/A) in the 3′ untranslated region of the human STAT6 gene (GeneBank Accession No. U16031). A novel PCR-RFLP method has been devised for this polymorphism using the amplification-created restriction site (ACRS) method. Allele frequencies in the UK Caucasian population were found to be 0.33 for allele A and 0.67 for allele G.

AB - We have identified a novel single nucleotide polymorphism at position 2964 (G/A) in the 3′ untranslated region of the human STAT6 gene (GeneBank Accession No. U16031). A novel PCR-RFLP method has been devised for this polymorphism using the amplification-created restriction site (ACRS) method. Allele frequencies in the UK Caucasian population were found to be 0.33 for allele A and 0.67 for allele G.

KW - Biallelic

KW - PCR-RFLP

KW - Polymorphism

KW - STAT6

UR - https://www.scopus.com/pages/publications/0034208088

M3 - Article

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VL - 1

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JO - Genes and Immunity

JF - Genes and Immunity

IS - 5

ER -

A novel PCR-RFLP assay for the detection of a polymorphism in the 3′ of STAT6 gene

Abstract

Keywords

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