A one-pot synthesis of 2-Aryl-4,5-anti-diphenyloxazolines

Jonathan Clayden, James Clayton, Rebecca A. Harvey, Ol'Ga KarlubÍková

    Research output: Contribution to journalArticlepeer-review

    Abstract

    A one-pot procedure for the synthesis of oxazolines was developed. An amino alcohol was coupled with benzoyl chlorides in the presence of triethylamine to produce a -hydroxyamide. Direct treatment with methanesulfonyl chloride forms oxazolines in good yields.
    Original languageEnglish
    Pages (from-to)2836-2838
    Number of pages2
    JournalSYNLETT
    Issue number17
    DOIs
    Publication statusPublished - 2009

    Keywords

    • Arenes
    • Auxiliary
    • Heterocycle substitutions
    • Oxazoline

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