A pooled analysis of Melanocytic nevus phenotype and the risk of cutaneous melanoma at different latitudes

Yu Mei Chang; Julia A. Newton-Bishop; D. Timothy Bishop; Bruce K. Armstrong; Veronique Bataille; Wilma Bergman; Marianne Berwick; Paige M. Bracci; J. Mark Elwood; Marc S. Ernstoff; Adèle C. Green; Nelleke A. Gruis; Elizabeth A. Holly; Christian Ingvar; Peter A. Kanetsky; Margaret R. Karagas; Loïc Le Marchand; Rona M. Mackie; Håkan Olsson; Anne Østerlind; Timothy R. Rebbeck; Kristian Reich; Peter Sasieni; Victor Siskind; Anthony J. Swerdlow; Linda Titus-Ernstoff; Michael S. Zens; Andreas Ziegler; Jennifer H. Barrett

doi:10.1002/ijc.23869

A pooled analysis of Melanocytic nevus phenotype and the risk of cutaneous melanoma at different latitudes

Yu Mei Chang, Julia A. Newton-Bishop, D. Timothy Bishop, Bruce K. Armstrong, Veronique Bataille, Wilma Bergman, Marianne Berwick, Paige M. Bracci, J. Mark Elwood, Marc S. Ernstoff, Adèle C. Green, Nelleke A. Gruis, Elizabeth A. Holly, Christian Ingvar, Peter A. Kanetsky, Margaret R. Karagas, Loïc Le Marchand, Rona M. Mackie, Håkan Olsson, Anne ØsterlindTimothy R. Rebbeck, Kristian Reich, Peter Sasieni, Victor Siskind, Anthony J. Swerdlow, Linda Titus-Ernstoff, Michael S. Zens, Andreas Ziegler, Jennifer H. Barrett

Research output: Contribution to journal › Article › peer-review

Abstract

An abnormal nevus phenotype is associated with an increased risk of melanoma. We report a pooled analysis conducted using individual nevus data from 15 case-control studies (5,421 melanoma cases and 6,966 controls). The aims were to quantify the risk better and to determine whether relative risk is varied by latitude. Bayesian unconditional logistic random coefficients models were employed to study the risk associated with nevus characteristics. Participants with whole body nevus counts in the highest of 4 population-based categories had a greatly increased risk of melanoma compared with those in the lowest category (pooled odds ratio (pOR) 6.9 (95% confidence interval (CI): 4.4,11.2) for those aged

Original language	English
Pages (from-to)	420-428
Number of pages	8
Journal	International Journal of Cancer
Volume	124
Issue number	2
DOIs	https://doi.org/10.1002/ijc.23869
Publication status	Published - 15 Jan 2009

Keywords

Bayesian
Latitude
Melanoma
Nevus
Pooled analysis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Chang, Y. M., Newton-Bishop, J. A., Bishop, D. T., Armstrong, B. K., Bataille, V., Bergman, W., Berwick, M., Bracci, P. M., Elwood, J. M., Ernstoff, M. S., Green, A. C., Gruis, N. A., Holly, E. A., Ingvar, C., Kanetsky, P. A., Karagas, M. R., Marchand, L. L., Mackie, R. M., Olsson, H., ... Barrett, J. H. (2009). A pooled analysis of Melanocytic nevus phenotype and the risk of cutaneous melanoma at different latitudes. International Journal of Cancer, 124(2), 420-428. https://doi.org/10.1002/ijc.23869

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title = "A pooled analysis of Melanocytic nevus phenotype and the risk of cutaneous melanoma at different latitudes",

abstract = "An abnormal nevus phenotype is associated with an increased risk of melanoma. We report a pooled analysis conducted using individual nevus data from 15 case-control studies (5,421 melanoma cases and 6,966 controls). The aims were to quantify the risk better and to determine whether relative risk is varied by latitude. Bayesian unconditional logistic random coefficients models were employed to study the risk associated with nevus characteristics. Participants with whole body nevus counts in the highest of 4 population-based categories had a greatly increased risk of melanoma compared with those in the lowest category (pooled odds ratio (pOR) 6.9 (95% confidence interval (CI): 4.4,11.2) for those aged",

keywords = "Bayesian, Latitude, Melanoma, Nevus, Pooled analysis",

author = "Chang, {Yu Mei} and Newton-Bishop, {Julia A.} and Bishop, {D. Timothy} and Armstrong, {Bruce K.} and Veronique Bataille and Wilma Bergman and Marianne Berwick and Bracci, {Paige M.} and Elwood, {J. Mark} and Ernstoff, {Marc S.} and Green, {Ad{\`e}le C.} and Gruis, {Nelleke A.} and Holly, {Elizabeth A.} and Christian Ingvar and Kanetsky, {Peter A.} and Karagas, {Margaret R.} and Marchand, {Lo{\"i}c Le} and Mackie, {Rona M.} and H{\aa}kan Olsson and Anne {\O}sterlind and Rebbeck, {Timothy R.} and Kristian Reich and Peter Sasieni and Victor Siskind and Swerdlow, {Anthony J.} and Linda Titus-Ernstoff and Zens, {Michael S.} and Andreas Ziegler and Barrett, {Jennifer H.}",

note = "P0-1 CA42101, CA, NCI NIH HHS, United StatesR01 CA059706-02, CA, NCI NIH HHS, United StatesR01-CA52345, CA, NCI NIH HHS, United States",

year = "2009",

month = jan,

day = "15",

doi = "10.1002/ijc.23869",

language = "English",

volume = "124",

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journal = "International Journal of Cancer",

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Chang, YM, Newton-Bishop, JA, Bishop, DT, Armstrong, BK, Bataille, V, Bergman, W, Berwick, M, Bracci, PM, Elwood, JM, Ernstoff, MS, Green, AC, Gruis, NA, Holly, EA, Ingvar, C, Kanetsky, PA, Karagas, MR, Marchand, LL, Mackie, RM, Olsson, H, Østerlind, A, Rebbeck, TR, Reich, K, Sasieni, P, Siskind, V, Swerdlow, AJ, Titus-Ernstoff, L, Zens, MS, Ziegler, A & Barrett, JH 2009, 'A pooled analysis of Melanocytic nevus phenotype and the risk of cutaneous melanoma at different latitudes', International Journal of Cancer, vol. 124, no. 2, pp. 420-428. https://doi.org/10.1002/ijc.23869

TY - JOUR

T1 - A pooled analysis of Melanocytic nevus phenotype and the risk of cutaneous melanoma at different latitudes

AU - Chang, Yu Mei

AU - Newton-Bishop, Julia A.

AU - Bishop, D. Timothy

AU - Armstrong, Bruce K.

AU - Bataille, Veronique

AU - Bergman, Wilma

AU - Berwick, Marianne

AU - Bracci, Paige M.

AU - Elwood, J. Mark

AU - Ernstoff, Marc S.

AU - Green, Adèle C.

AU - Gruis, Nelleke A.

AU - Holly, Elizabeth A.

AU - Ingvar, Christian

AU - Kanetsky, Peter A.

AU - Karagas, Margaret R.

AU - Marchand, Loïc Le

AU - Mackie, Rona M.

AU - Olsson, Håkan

AU - Østerlind, Anne

AU - Rebbeck, Timothy R.

AU - Reich, Kristian

AU - Sasieni, Peter

AU - Siskind, Victor

AU - Swerdlow, Anthony J.

AU - Titus-Ernstoff, Linda

AU - Zens, Michael S.

AU - Ziegler, Andreas

AU - Barrett, Jennifer H.

N1 - P0-1 CA42101, CA, NCI NIH HHS, United StatesR01 CA059706-02, CA, NCI NIH HHS, United StatesR01-CA52345, CA, NCI NIH HHS, United States

PY - 2009/1/15

Y1 - 2009/1/15

N2 - An abnormal nevus phenotype is associated with an increased risk of melanoma. We report a pooled analysis conducted using individual nevus data from 15 case-control studies (5,421 melanoma cases and 6,966 controls). The aims were to quantify the risk better and to determine whether relative risk is varied by latitude. Bayesian unconditional logistic random coefficients models were employed to study the risk associated with nevus characteristics. Participants with whole body nevus counts in the highest of 4 population-based categories had a greatly increased risk of melanoma compared with those in the lowest category (pooled odds ratio (pOR) 6.9 (95% confidence interval (CI): 4.4,11.2) for those aged

AB - An abnormal nevus phenotype is associated with an increased risk of melanoma. We report a pooled analysis conducted using individual nevus data from 15 case-control studies (5,421 melanoma cases and 6,966 controls). The aims were to quantify the risk better and to determine whether relative risk is varied by latitude. Bayesian unconditional logistic random coefficients models were employed to study the risk associated with nevus characteristics. Participants with whole body nevus counts in the highest of 4 population-based categories had a greatly increased risk of melanoma compared with those in the lowest category (pooled odds ratio (pOR) 6.9 (95% confidence interval (CI): 4.4,11.2) for those aged

KW - Bayesian

KW - Latitude

KW - Melanoma

KW - Nevus

KW - Pooled analysis

U2 - 10.1002/ijc.23869

DO - 10.1002/ijc.23869

M3 - Article

C2 - 18792098

SN - 0020-7136

VL - 124

SP - 420

EP - 428

JO - International Journal of Cancer

JF - International Journal of Cancer

IS - 2

ER -

A pooled analysis of Melanocytic nevus phenotype and the risk of cutaneous melanoma at different latitudes

Abstract

Keywords

UN SDGs

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