A prospective study of serum lipoproteins after coronary artery bypass surgery

N. Shaukat, S. S. Ashraf, M. I. Mackness, A. D. Mbewu, D. Bhatnagar, P. N. Durrington

    Research output: Contribution to journalArticlepeer-review

    Abstract

    We examined the acute and long-term effects of coronary artery bypass (CABG) surgery on serum lipid, lipoprotein and apolipoprotein levels. One series of 34 patients having CABG surgery was studied pre-operatively and for six weeks afterwards, and another 22 patients were investigated before and two years after CABG surgery. None of the patients studied received any lipid-lowering drug therapy or specific dietary advice. In both groups, pre-operative serum lipoprotein (a) (Lp(a)) and serum triglyceride concentrations were raised and serum high-density lipoprotein (HDL) cholesterol and apolipoprotein Al (apo Al) were low compared to healthy people. Acutely, there were profound decreases of 40-60% in the serum levels of cholesterol (p
    Original languageEnglish
    Pages (from-to)539-545
    Number of pages6
    JournalQuarterly Journal of Medicine
    Volume87
    Issue number9
    Publication statusPublished - 1994

    Keywords

    • Adult
    • Aged
    • analysis: Apolipoproteins B
    • blood: Cholesterol
    • blood: Cholesterol, HDL
    • Coronary Artery Bypass
    • blood: Coronary Disease
    • Female
    • Follow-Up Studies
    • Humans
    • blood: Lipoprotein(a)
    • blood: Lipoproteins
    • Male
    • Middle Aged
    • Postoperative Period
    • Prospective Studies
    • blood: Triglycerides

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