A prospective study of serum lipoproteins after coronary artery bypass surgery

N. Shaukat; S. S. Ashraf; M. I. Mackness; A. D. Mbewu; D. Bhatnagar; P. N. Durrington

A prospective study of serum lipoproteins after coronary artery bypass surgery

N. Shaukat
, S. S. Ashraf
, M. I. Mackness
, A. D. Mbewu
, D. Bhatnagar
, P. N. Durrington

Research output: Contribution to journal › Article › peer-review

Abstract

We examined the acute and long-term effects of coronary artery bypass (CABG) surgery on serum lipid, lipoprotein and apolipoprotein levels. One series of 34 patients having CABG surgery was studied pre-operatively and for six weeks afterwards, and another 22 patients were investigated before and two years after CABG surgery. None of the patients studied received any lipid-lowering drug therapy or specific dietary advice. In both groups, pre-operative serum lipoprotein (a) (Lp(a)) and serum triglyceride concentrations were raised and serum high-density lipoprotein (HDL) cholesterol and apolipoprotein Al (apo Al) were low compared to healthy people. Acutely, there were profound decreases of 40-60% in the serum levels of cholesterol (p

Original language	English
Pages (from-to)	539-545
Number of pages	6
Journal	Quarterly Journal of Medicine
Volume	87
Issue number	9
Publication status	Published - 1994

Keywords

Adult
Aged
analysis: Apolipoproteins B
blood: Cholesterol
blood: Cholesterol, HDL
Coronary Artery Bypass
blood: Coronary Disease
Female
Follow-Up Studies
Humans
blood: Lipoprotein(a)
blood: Lipoproteins
Male
Middle Aged
Postoperative Period
Prospective Studies
blood: Triglycerides

Cite this

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title = "A prospective study of serum lipoproteins after coronary artery bypass surgery",

abstract = "We examined the acute and long-term effects of coronary artery bypass (CABG) surgery on serum lipid, lipoprotein and apolipoprotein levels. One series of 34 patients having CABG surgery was studied pre-operatively and for six weeks afterwards, and another 22 patients were investigated before and two years after CABG surgery. None of the patients studied received any lipid-lowering drug therapy or specific dietary advice. In both groups, pre-operative serum lipoprotein (a) (Lp(a)) and serum triglyceride concentrations were raised and serum high-density lipoprotein (HDL) cholesterol and apolipoprotein Al (apo Al) were low compared to healthy people. Acutely, there were profound decreases of 40-60\% in the serum levels of cholesterol (p",

keywords = "Adult, Aged, analysis: Apolipoproteins B, blood: Cholesterol, blood: Cholesterol, HDL, Coronary Artery Bypass, blood: Coronary Disease, Female, Follow-Up Studies, Humans, blood: Lipoprotein(a), blood: Lipoproteins, Male, Middle Aged, Postoperative Period, Prospective Studies, blood: Triglycerides",

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year = "1994",

language = "English",

volume = "87",

pages = "539--545",

journal = "Quarterly Journal of Medicine",

publisher = "Oxford University Press",

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TY - JOUR

T1 - A prospective study of serum lipoproteins after coronary artery bypass surgery

AU - Shaukat, N.

AU - Ashraf, S. S.

AU - Mackness, M. I.

AU - Mbewu, A. D.

AU - Bhatnagar, D.

AU - Durrington, P. N.

PY - 1994

Y1 - 1994

N2 - We examined the acute and long-term effects of coronary artery bypass (CABG) surgery on serum lipid, lipoprotein and apolipoprotein levels. One series of 34 patients having CABG surgery was studied pre-operatively and for six weeks afterwards, and another 22 patients were investigated before and two years after CABG surgery. None of the patients studied received any lipid-lowering drug therapy or specific dietary advice. In both groups, pre-operative serum lipoprotein (a) (Lp(a)) and serum triglyceride concentrations were raised and serum high-density lipoprotein (HDL) cholesterol and apolipoprotein Al (apo Al) were low compared to healthy people. Acutely, there were profound decreases of 40-60% in the serum levels of cholesterol (p

AB - We examined the acute and long-term effects of coronary artery bypass (CABG) surgery on serum lipid, lipoprotein and apolipoprotein levels. One series of 34 patients having CABG surgery was studied pre-operatively and for six weeks afterwards, and another 22 patients were investigated before and two years after CABG surgery. None of the patients studied received any lipid-lowering drug therapy or specific dietary advice. In both groups, pre-operative serum lipoprotein (a) (Lp(a)) and serum triglyceride concentrations were raised and serum high-density lipoprotein (HDL) cholesterol and apolipoprotein Al (apo Al) were low compared to healthy people. Acutely, there were profound decreases of 40-60% in the serum levels of cholesterol (p

KW - Adult

KW - Aged

KW - analysis: Apolipoproteins B

KW - blood: Cholesterol

KW - blood: Cholesterol, HDL

KW - Coronary Artery Bypass

KW - blood: Coronary Disease

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - blood: Lipoprotein(a)

KW - blood: Lipoproteins

KW - Male

KW - Middle Aged

KW - Postoperative Period

KW - Prospective Studies

KW - blood: Triglycerides

M3 - Article

VL - 87

SP - 539

EP - 545

JO - Quarterly Journal of Medicine

JF - Quarterly Journal of Medicine

IS - 9

ER -

A prospective study of serum lipoproteins after coronary artery bypass surgery

Abstract

Keywords

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