A QconCAT informatics pipeline for the analysis, visualization and sharing of absolute quantitative proteomics data

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Abstract

Absolute protein concentration determination is becoming increasingly important in a number of fields including diagnostics, biomarker discovery and systems biology modeling. The recently introduced quantification concatamer methodology provides a novel approach to performing such determinations, and it has been applied to both microbial and mammalian systems. While a number of software tools exist for performing analyses of quantitative data generated by related methodologies such as SILAC, there is currently no analysis package dedicated to the quantification concatamer approach. Furthermore, most tools that are currently available in the field of quantitative proteomics do not manage storage and dissemination of such data sets. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Original languageEnglish
Pages (from-to)329-333
Number of pages4
JournalProteomics
Volume11
Issue number2
Early online date30 Nov 2010
DOIs
Publication statusPublished - Jan 2011

Keywords

  • bioinformatics
  • data analysis
  • data management
  • quantification concatamer
  • quantitation

Research Beacons, Institutes and Platforms

  • Manchester Institute of Biotechnology

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