A review of attenuation correction techniques for tissue fluorescence

Robert S. Bradley, Maureen S. Thorniley

Research output: Contribution to journalArticlepeer-review


Fluorescence intensity measurements have the potential to facilitate the diagnoses of many pathological conditions. However, accurate interpretation of the measurements is complicated by the distorting effects of tissue scattering and absorption. Consequently, different techniques have been developed to attempt to compensate for these effects. This paper reviews currently available correction techniques with emphasis on clinical application and consideration given to the intrinsic accuracy and limitations of each technique. © 2005 The Royal Society.
Original languageEnglish
Pages (from-to)1-13
Number of pages12
JournalJournal of the Royal Society Interface
Issue number6
Publication statusPublished - 22 Feb 2006


  • Absorption
  • Correction techniques
  • Scattering
  • Tissue fluorescence


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