A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977

D. J. Dixon; S. V. Ley; D. J. Reynolds; M. S. Chorghade

doi:10.1080/00397910008087245

A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977

D. J. Dixon
, S. V. Ley
, D. J. Reynolds
, M. S. Chorghade

Research output: Contribution to journal › Article › peer-review

Abstract

A short and efficient synthesis of the potent 5-lipoxygenase inhibitor CMI-977 has been accomplished, utilising an oxygen to carbon rearrangement of an anomerically linked alkynyl stannane tetrahydrofuranyl ether derivative as the key step.

Original language	English
Pages (from-to)	1043-1053
Number of pages	10
Journal	Indian Journal of Chemistry. Section B
Volume	40
Issue number	11
DOIs	https://doi.org/10.1080/00397910008087245
Publication status	Published - 2001

Keywords

Crystal structure; Molecular structure; Rearrangement (stereoselective prepn. of 5-lipoxygenase inhibitor CMI-977)

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10.1080/00397910008087245

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title = "A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977",

abstract = "A short and efficient synthesis of the potent 5-lipoxygenase inhibitor CMI-977 has been accomplished, utilising an oxygen to carbon rearrangement of an anomerically linked alkynyl stannane tetrahydrofuranyl ether derivative as the key step.",

keywords = "Crystal structure; Molecular structure; Rearrangement (stereoselective prepn. of 5-lipoxygenase inhibitor CMI-977)",

author = "Dixon, \{D. J.\} and Ley, \{S. V.\} and Reynolds, \{D. J.\} and Chorghade, \{M. S.\}",

year = "2001",

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pages = "1043--1053",

journal = "Indian Journal of Chemistry. Section B ",

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T1 - A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977

AU - Dixon, D. J.

AU - Ley, S. V.

AU - Reynolds, D. J.

AU - Chorghade, M. S.

PY - 2001

Y1 - 2001

N2 - A short and efficient synthesis of the potent 5-lipoxygenase inhibitor CMI-977 has been accomplished, utilising an oxygen to carbon rearrangement of an anomerically linked alkynyl stannane tetrahydrofuranyl ether derivative as the key step.

AB - A short and efficient synthesis of the potent 5-lipoxygenase inhibitor CMI-977 has been accomplished, utilising an oxygen to carbon rearrangement of an anomerically linked alkynyl stannane tetrahydrofuranyl ether derivative as the key step.

KW - Crystal structure; Molecular structure; Rearrangement (stereoselective prepn. of 5-lipoxygenase inhibitor CMI-977)

U2 - 10.1080/00397910008087245

DO - 10.1080/00397910008087245

M3 - Article

SN - 0975-0983

VL - 40

SP - 1043

EP - 1053

JO - Indian Journal of Chemistry. Section B

JF - Indian Journal of Chemistry. Section B

IS - 11

ER -

A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977

Abstract

Keywords

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