TY - JOUR
T1 - A Six-Crossing [2]Catenane with Twisted Rings (a Molecular 6-3-2 Link), and a Molecular Granny Knot
AU - Leigh, David
AU - Danon, Jonathan
AU - Pisano, Simone
AU - Valero, Alberto
AU - Vitorica-yrezabal, Iñigo J.
PY - 2018
Y1 - 2018
N2 - A molecular 6_3^2 link (a six crossing, doubly interlocked, [2]catenane with twisted rings) and a 31#31 granny knot (a composite knot made up of two trefoil tangles of the same handedness) were constructed by ring‐closing olefin metathesis of an iron(II)‐coordinated 2×2 interwoven grid. The connections were directed by pendant phenyl groups to be between proximal ligand ends on the same faces of the grid. The 6_3^2 link was separated from the topoisomeric granny knot by recycling size‐exclusion chromatography. The identity of each topoisomer was determined by tandem mass spectrometry and the structure of the 6_3^2 link confirmed by X‐ray crystallography, which revealed two 82‐membered macrocycles, each in figure‐of‐eight conformations, linked through both pairs of loops.
AB - A molecular 6_3^2 link (a six crossing, doubly interlocked, [2]catenane with twisted rings) and a 31#31 granny knot (a composite knot made up of two trefoil tangles of the same handedness) were constructed by ring‐closing olefin metathesis of an iron(II)‐coordinated 2×2 interwoven grid. The connections were directed by pendant phenyl groups to be between proximal ligand ends on the same faces of the grid. The 6_3^2 link was separated from the topoisomeric granny knot by recycling size‐exclusion chromatography. The identity of each topoisomer was determined by tandem mass spectrometry and the structure of the 6_3^2 link confirmed by X‐ray crystallography, which revealed two 82‐membered macrocycles, each in figure‐of‐eight conformations, linked through both pairs of loops.
U2 - 10.1002/anie.201807135
DO - 10.1002/anie.201807135
M3 - Article
SN - 1433-7851
JO - Angewandte Chemie International Edition
JF - Angewandte Chemie International Edition
ER -