A Study of Photochromic Azobenzene Liquid Crystals as Controlled Release Drug Delivery Systems

Samantha J. Watson; Helen F. Gleeson; Antony D'Emanuele; Svetlana Serak; Vladimir Grozhik

A Study of Photochromic Azobenzene Liquid Crystals as Controlled Release Drug Delivery Systems

Samantha J. Watson
, Helen F. Gleeson
, Antony D'Emanuele
, Svetlana Serak
, Vladimir Grozhik

Research output: Chapter in Book/Conference proceeding › Conference contribution

Abstract

Photochemically induced liquid crystal phase transitions are considered in the context of photo-induced controlled drug release. The model materials examined are the homologous series of 4-n-butyl-4′-n-alkoxyazobenzenes (BAABs). Radiation from a low power argon ion laser is used to induce the photochromic trans-cis isomerisation of the materials, resulting in an isothermal phase transition from the nematic to the isotropic phase. The response times are examined with respect to temperature, cell thickness and homologue. The data are discussed in the context of such systems' usefulness and ultimate applicability in photo-responsive drug delivery devices.

Original language	English
Title of host publication	Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals\|Mol Cryst Liq Cryst Sci Technol Sect A Mol Crys Liq Cryst
Pages	375-382
Number of pages	7
Volume	331
Publication status	Published - 1999

Keywords

Azobenzene
Drug release
Liquid crystal
Photochromic

Cite this

Watson, S. J., Gleeson, H. F., D'Emanuele, A., Serak, S., & Grozhik, V. (1999). A Study of Photochromic Azobenzene Liquid Crystals as Controlled Release Drug Delivery Systems. In Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals|Mol Cryst Liq Cryst Sci Technol Sect A Mol Crys Liq Cryst (Vol. 331, pp. 375-382)

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abstract = "Photochemically induced liquid crystal phase transitions are considered in the context of photo-induced controlled drug release. The model materials examined are the homologous series of 4-n-butyl-4′-n-alkoxyazobenzenes (BAABs). Radiation from a low power argon ion laser is used to induce the photochromic trans-cis isomerisation of the materials, resulting in an isothermal phase transition from the nematic to the isotropic phase. The response times are examined with respect to temperature, cell thickness and homologue. The data are discussed in the context of such systems' usefulness and ultimate applicability in photo-responsive drug delivery devices.",

keywords = "Azobenzene, Drug release, Liquid crystal, Photochromic",

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year = "1999",

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A Study of Photochromic Azobenzene Liquid Crystals as Controlled Release Drug Delivery Systems. / Watson, Samantha J.; Gleeson, Helen F.; D'Emanuele, Antony et al.
Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals|Mol Cryst Liq Cryst Sci Technol Sect A Mol Crys Liq Cryst. Vol. 331 1999. p. 375-382.

Research output: Chapter in Book/Conference proceeding › Conference contribution

TY - GEN

T1 - A Study of Photochromic Azobenzene Liquid Crystals as Controlled Release Drug Delivery Systems

AU - Watson, Samantha J.

AU - Gleeson, Helen F.

AU - D'Emanuele, Antony

AU - Serak, Svetlana

AU - Grozhik, Vladimir

PY - 1999

Y1 - 1999

N2 - Photochemically induced liquid crystal phase transitions are considered in the context of photo-induced controlled drug release. The model materials examined are the homologous series of 4-n-butyl-4′-n-alkoxyazobenzenes (BAABs). Radiation from a low power argon ion laser is used to induce the photochromic trans-cis isomerisation of the materials, resulting in an isothermal phase transition from the nematic to the isotropic phase. The response times are examined with respect to temperature, cell thickness and homologue. The data are discussed in the context of such systems' usefulness and ultimate applicability in photo-responsive drug delivery devices.

AB - Photochemically induced liquid crystal phase transitions are considered in the context of photo-induced controlled drug release. The model materials examined are the homologous series of 4-n-butyl-4′-n-alkoxyazobenzenes (BAABs). Radiation from a low power argon ion laser is used to induce the photochromic trans-cis isomerisation of the materials, resulting in an isothermal phase transition from the nematic to the isotropic phase. The response times are examined with respect to temperature, cell thickness and homologue. The data are discussed in the context of such systems' usefulness and ultimate applicability in photo-responsive drug delivery devices.

KW - Azobenzene

KW - Drug release

KW - Liquid crystal

KW - Photochromic

M3 - Conference contribution

VL - 331

SP - 375

EP - 382

BT - Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals|Mol Cryst Liq Cryst Sci Technol Sect A Mol Crys Liq Cryst

ER -

A Study of Photochromic Azobenzene Liquid Crystals as Controlled Release Drug Delivery Systems

Abstract

Keywords

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