A theoretical study of the parent NH-benzazoles (benzimidazoles, indazoles and benzotriazoles): Geometries, energies, acidity and basicity, NMR properties and molecular electrostatic potentials

Ibon Alkorta*, Goar Sánchez-Sanz, Cristina Trujillo, José Elguero, Rosa M. Claramunt

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The three parent NH-benzazoles, benzimidazole, indazole and benzotriazole, have been studied theoretically at the B3LYP/6-311++G(d,p) level. Optimized geometries have been compared with those obtained by X-ray crystallography, energies with studies about tautomerism, acid-base properties with pK as, and chemical shifts with those reported in the literature. As aromaticity probe, Schleyer's Nuclear Independent Chemical Shifts (NICS) were used and represented in two 3D isosurfaces of the electron density.

Original languageEnglish
Pages (from-to)85-106
Number of pages22
JournalArkivoc
Volume2012
Issue number2
DOIs
Publication statusPublished - 15 Aug 2012

Keywords

  • Acid-base equilibria
  • Benzimidazole
  • Benzotriazole
  • Carbenes
  • Indazole
  • NMR
  • Nuclear Independent Chemical Shifts
  • Tautomerism

Fingerprint

Dive into the research topics of 'A theoretical study of the parent NH-benzazoles (benzimidazoles, indazoles and benzotriazoles): Geometries, energies, acidity and basicity, NMR properties and molecular electrostatic potentials'. Together they form a unique fingerprint.

Cite this