Absolute membrane protein abundance of P-glycoprotein, breast cancer resistance protein, and multidrug resistance proteins in term human placenta tissue and commonly used cell systems: Application in physiologically based pharmacokinetic modeling of placental drug disposition

Zubida M. Al-Majdoub; Jolien J.M. Freriksen; Angela Colbers; Jeroen van den Heuvel; Jan Koenderink; Khaled Abduljalil; Brahim Achour; Jill Barber; Rick Greupink; Amin Rostami-Hodjegan

doi:10.1124/dmd.124.001824

Absolute membrane protein abundance of P-glycoprotein, breast cancer resistance protein, and multidrug resistance proteins in term human placenta tissue and commonly used cell systems: Application in physiologically based pharmacokinetic modeling of placental drug disposition

Zubida M. Al-Majdoub, Jolien J.M. Freriksen, Angela Colbers, Jeroen van den Heuvel, Jan Koenderink, Khaled Abduljalil, Brahim Achour, Jill Barber, Rick Greupink, Amin Rostami-Hodjegan

Pharmacy

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	100007
Journal	Drug Metabolism and Disposition
Volume	53
Issue number	1
DOIs	https://doi.org/10.1124/dmd.124.001824
Publication status	Published - 1 Jan 2025

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10.1124/dmd.124.001824Licence: CC BY-NC-ND

https://linkinghub.elsevier.com/retrieve/pii/S0090955624148477

Cite this

Al-Majdoub, Z. M., Freriksen, J. J. M., Colbers, A., van den Heuvel, J., Koenderink, J., Abduljalil, K., Achour, B., Barber, J., Greupink, R., & Rostami-Hodjegan, A. (2025). Absolute membrane protein abundance of P-glycoprotein, breast cancer resistance protein, and multidrug resistance proteins in term human placenta tissue and commonly used cell systems: Application in physiologically based pharmacokinetic modeling of placental drug disposition. Drug Metabolism and Disposition, 53(1), 100007. https://doi.org/10.1124/dmd.124.001824

Al-Majdoub, Zubida M. ; Freriksen, Jolien J.M. ; Colbers, Angela et al. / Absolute membrane protein abundance of P-glycoprotein, breast cancer resistance protein, and multidrug resistance proteins in term human placenta tissue and commonly used cell systems: Application in physiologically based pharmacokinetic modeling of placental drug disposition. In: Drug Metabolism and Disposition. 2025 ; Vol. 53, No. 1. pp. 100007.

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Al-Majdoub, ZM, Freriksen, JJM, Colbers, A, van den Heuvel, J, Koenderink, J, Abduljalil, K, Achour, B, Barber, J, Greupink, R & Rostami-Hodjegan, A 2025, 'Absolute membrane protein abundance of P-glycoprotein, breast cancer resistance protein, and multidrug resistance proteins in term human placenta tissue and commonly used cell systems: Application in physiologically based pharmacokinetic modeling of placental drug disposition', Drug Metabolism and Disposition, vol. 53, no. 1, pp. 100007. https://doi.org/10.1124/dmd.124.001824

Absolute membrane protein abundance of P-glycoprotein, breast cancer resistance protein, and multidrug resistance proteins in term human placenta tissue and commonly used cell systems: Application in physiologically based pharmacokinetic modeling of placental drug disposition. / Al-Majdoub, Zubida M.; Freriksen, Jolien J.M.; Colbers, Angela et al.
In: Drug Metabolism and Disposition, Vol. 53, No. 1, 01.01.2025, p. 100007.

Research output: Contribution to journal › Article › peer-review

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AU - Al-Majdoub, Zubida M.

AU - Freriksen, Jolien J.M.

AU - Colbers, Angela

AU - van den Heuvel, Jeroen

AU - Koenderink, Jan

AU - Abduljalil, Khaled

AU - Achour, Brahim

AU - Barber, Jill

AU - Greupink, Rick

AU - Rostami-Hodjegan, Amin

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Al-Majdoub ZM, Freriksen JJM, Colbers A, van den Heuvel J, Koenderink J, Abduljalil K et al. Absolute membrane protein abundance of P-glycoprotein, breast cancer resistance protein, and multidrug resistance proteins in term human placenta tissue and commonly used cell systems: Application in physiologically based pharmacokinetic modeling of placental drug disposition. Drug Metabolism and Disposition. 2025 Jan 1;53(1):100007. doi: 10.1124/dmd.124.001824