Accurate Extraction of Nanometer Distances in Multimers by Pulse EPR

Silvia Valera; Katrin Ackermann; Christos Pliotas; Hexian Huang; James H. Naismith; Bela E. Bode

doi:10.1002/chem.201505143

Accurate Extraction of Nanometer Distances in Multimers by Pulse EPR

Silvia Valera, Katrin Ackermann, Christos Pliotas, Hexian Huang, James H. Naismith, Bela E. Bode

Division of Molecular & Cellular Function (L5)

Research output: Contribution to journal › Article › peer-review

Abstract

Pulse electron paramagnetic resonance (EPR) is gaining increasing importance in structural biology. The PELDOR (pulsed electron–electron double resonance) method allows extracting distance information on the nanometer scale. Here, we demonstrate the efficient extraction of distances from multimeric systems such as membrane-embedded ion channels where data analysis is commonly hindered by multi-spin effects.

Original language	English
Pages (from-to)	4700-4703
Number of pages	4
Journal	Chemistry - A European Journal
Volume	22
Issue number	14
Early online date	11 Feb 2016
DOIs	https://doi.org/10.1002/chem.201505143
Publication status	Published - 24 Mar 2016

Access to Document

10.1002/chem.201505143

Cite this

@article{e3b49d5d4a7448f3bffd7970c18477b7,

title = "Accurate Extraction of Nanometer Distances in Multimers by Pulse EPR",

abstract = "Pulse electron paramagnetic resonance (EPR) is gaining increasing importance in structural biology. The PELDOR (pulsed electron–electron double resonance) method allows extracting distance information on the nanometer scale. Here, we demonstrate the efficient extraction of distances from multimeric systems such as membrane-embedded ion channels where data analysis is commonly hindered by multi-spin effects.",

author = "Silvia Valera and Katrin Ackermann and Christos Pliotas and Hexian Huang and Naismith, {James H.} and Bode, {Bela E.}",

year = "2016",

month = mar,

day = "24",

doi = "10.1002/chem.201505143",

language = "English",

volume = "22",

pages = "4700--4703",

journal = "Chemistry - A European Journal",

issn = "0947-6539",

publisher = "John Wiley & Sons Ltd",

number = "14",

}

TY - JOUR

T1 - Accurate Extraction of Nanometer Distances in Multimers by Pulse EPR

AU - Valera, Silvia

AU - Ackermann, Katrin

AU - Pliotas, Christos

AU - Huang, Hexian

AU - Naismith, James H.

AU - Bode, Bela E.

PY - 2016/3/24

Y1 - 2016/3/24

N2 - Pulse electron paramagnetic resonance (EPR) is gaining increasing importance in structural biology. The PELDOR (pulsed electron–electron double resonance) method allows extracting distance information on the nanometer scale. Here, we demonstrate the efficient extraction of distances from multimeric systems such as membrane-embedded ion channels where data analysis is commonly hindered by multi-spin effects.

AB - Pulse electron paramagnetic resonance (EPR) is gaining increasing importance in structural biology. The PELDOR (pulsed electron–electron double resonance) method allows extracting distance information on the nanometer scale. Here, we demonstrate the efficient extraction of distances from multimeric systems such as membrane-embedded ion channels where data analysis is commonly hindered by multi-spin effects.

UR - https://doi.org/10.1002/chem.201505143

U2 - 10.1002/chem.201505143

DO - 10.1002/chem.201505143

M3 - Article

SN - 0947-6539

VL - 22

SP - 4700

EP - 4703

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

IS - 14

ER -

Accurate Extraction of Nanometer Distances in Multimers by Pulse EPR

Abstract

Access to Document

Other files and links

Fingerprint

Cite this