Acne: Inflammation

Mark D. Farrar; Eileen Ingham

doi:10.1016/j.clindermatol.2004.03.006

Acne: Inflammation

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Abstract

The inflammatory stage of acne vulgaris is usually of greatest concern to the patient. A number of morphologically different inflammatory lesions may form that can be painful and unsightly. In 30% of patients, such lesions lead to scarring.1 Inflammatory acne and acne scarring can have significant psychological effects on the patient, including depression, anxiety, and poor self-image.2 Although inflammatory acne has been well characterized clinically, the mechanisms by which inflammatory lesions arise are still poorly understood. The human skin commensal bacterium, Propionibacterium acnes, has long been associated with inflammatory acne. This organism has been implicated over and above all of the other cutaneous microflora in contributing to the inflammatory response characteristic of acne. However, its precise role in the disease and its interaction with the human immune system remain to be elucidated.

Original language	English
Pages (from-to)	380-384
Number of pages	4
Journal	Clinics in Dermatology
Volume	22
Issue number	5
DOIs	https://doi.org/10.1016/j.clindermatol.2004.03.006
Publication status	Published - Sept 2004

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10.1016/j.clindermatol.2004.03.006

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title = "Acne: Inflammation",

abstract = "The inflammatory stage of acne vulgaris is usually of greatest concern to the patient. A number of morphologically different inflammatory lesions may form that can be painful and unsightly. In 30% of patients, such lesions lead to scarring.1 Inflammatory acne and acne scarring can have significant psychological effects on the patient, including depression, anxiety, and poor self-image.2 Although inflammatory acne has been well characterized clinically, the mechanisms by which inflammatory lesions arise are still poorly understood. The human skin commensal bacterium, Propionibacterium acnes, has long been associated with inflammatory acne. This organism has been implicated over and above all of the other cutaneous microflora in contributing to the inflammatory response characteristic of acne. However, its precise role in the disease and its interaction with the human immune system remain to be elucidated.",

author = "Farrar, {Mark D.} and Eileen Ingham",

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doi = "10.1016/j.clindermatol.2004.03.006",

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issn = "1879-1131",

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T1 - Acne: Inflammation

AU - Farrar, Mark D.

AU - Ingham, Eileen

PY - 2004/9

Y1 - 2004/9

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AB - The inflammatory stage of acne vulgaris is usually of greatest concern to the patient. A number of morphologically different inflammatory lesions may form that can be painful and unsightly. In 30% of patients, such lesions lead to scarring.1 Inflammatory acne and acne scarring can have significant psychological effects on the patient, including depression, anxiety, and poor self-image.2 Although inflammatory acne has been well characterized clinically, the mechanisms by which inflammatory lesions arise are still poorly understood. The human skin commensal bacterium, Propionibacterium acnes, has long been associated with inflammatory acne. This organism has been implicated over and above all of the other cutaneous microflora in contributing to the inflammatory response characteristic of acne. However, its precise role in the disease and its interaction with the human immune system remain to be elucidated.

U2 - 10.1016/j.clindermatol.2004.03.006

DO - 10.1016/j.clindermatol.2004.03.006

M3 - Article

C2 - 15556722

SN - 1879-1131

VL - 22

SP - 380

EP - 384

JO - Clinics in Dermatology

JF - Clinics in Dermatology

IS - 5

ER -

Acne: Inflammation

Abstract

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