Acute care bundles should be used for patients with intracerebral haemorrhage: An expert consensus statement

Adrian R Parry-Jones, Susann J Järhult, Natalie Kreitzer, Andrea Morotti, Danilo Toni, David Seiffge, Alexander David Mendelow, Hiren Patel, Hens Bart Brouwers, Catharina Jm Klijn, Thorsten Steiner, Walter Brian Gibler, Joshua N Goldstein

Research output: Contribution to journalReview articlepeer-review


PURPOSE: Intracerebral haemorrhage (ICH) is the most devastating form of stroke and a major cause of disability. Clinical trials of individual therapies have failed to definitively establish a specific beneficial treatment. However, clinical trials of introducing care bundles, with multiple therapies provided in parallel, appear to clearly reduce morbidity and mortality. Currently, not enough patients receive these interventions in the acute phase.

METHODS: We convened an expert group to discuss best practices in ICH and to develop recommendations for bundled care that can be delivered in all settings that treat acute ICH, with a focus on European healthcare systems.

FINDINGS: In this consensus paper, we argue for widespread implementation of formalised care bundles in ICH, including specific metrics for time to treatment and criteria for the consideration of neurosurgical therapy.

DISCUSSION: There is an extraordinary opportunity to improve clinical care and clinical outcomes in this devastating disease. Substantial evidence already exists for a range of therapies that can and should be implemented now.

Original languageEnglish
Article number23969873231220235
JournalEuropean Stroke Journal
Early online date27 Dec 2023
Publication statusPublished - 27 Dec 2023


  • Intracerebral haemorrhage
  • blood pressure
  • care bundles
  • fever
  • haematoma evacuation
  • hyperglycaemia
  • oral anticoagulants


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