Addition of lithiated tertiary aromatic amides to epoxides and aziridines: Asymmetric synthesis of (S)-(+)-mellein

Jonathan Clayden; Christopher C. Stimson; Madeleine Helliwell; Martine Keenan

doi:10.1055/s-2006-939043

Addition of lithiated tertiary aromatic amides to epoxides and aziridines: Asymmetric synthesis of (S)-(+)-mellein

Jonathan Clayden, Christopher C. Stimson, Madeleine Helliwell, Martine Keenan

Research output: Contribution to journal › Article › peer-review

Abstract

Addition of ortholithiated or laterally lithiated amides to epoxides or aziridines provides, in some cases stereoselectively, products which may cyclise to yield benzopyranones in good enantiomeric excess. © Georg Thieme Verlag Stuttgart.

Original language	English
Pages (from-to)	873-876
Number of pages	3
Journal	SYNLETT
Issue number	6
DOIs	https://doi.org/10.1055/s-2006-939043
Publication status	Published - 4 Apr 2006

Keywords

Benzopyranone
Directed metallation
Epoxide
Isochromanone
Lithiation
Synthesis

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10.1055/s-2006-939043

Cite this

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title = "Addition of lithiated tertiary aromatic amides to epoxides and aziridines: Asymmetric synthesis of (S)-(+)-mellein",

abstract = "Addition of ortholithiated or laterally lithiated amides to epoxides or aziridines provides, in some cases stereoselectively, products which may cyclise to yield benzopyranones in good enantiomeric excess. {\textcopyright} Georg Thieme Verlag Stuttgart.",

keywords = "Benzopyranone, Directed metallation, Epoxide, Isochromanone, Lithiation, Synthesis",

author = "Jonathan Clayden and Stimson, {Christopher C.} and Madeleine Helliwell and Martine Keenan",

year = "2006",

month = apr,

day = "4",

doi = "10.1055/s-2006-939043",

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AU - Clayden, Jonathan

AU - Stimson, Christopher C.

AU - Helliwell, Madeleine

AU - Keenan, Martine

PY - 2006/4/4

Y1 - 2006/4/4

N2 - Addition of ortholithiated or laterally lithiated amides to epoxides or aziridines provides, in some cases stereoselectively, products which may cyclise to yield benzopyranones in good enantiomeric excess. © Georg Thieme Verlag Stuttgart.

AB - Addition of ortholithiated or laterally lithiated amides to epoxides or aziridines provides, in some cases stereoselectively, products which may cyclise to yield benzopyranones in good enantiomeric excess. © Georg Thieme Verlag Stuttgart.

KW - Benzopyranone

KW - Directed metallation

KW - Epoxide

KW - Isochromanone

KW - Lithiation

KW - Synthesis

UR - https://www.ccdc.cam.ac.uk/structures/search?id=doi:10.5517/cc9nsc2&sid=DataCite

U2 - 10.1055/s-2006-939043

DO - 10.1055/s-2006-939043

M3 - Article

SN - 1437-2096

SP - 873

EP - 876

JO - SYNLETT

JF - SYNLETT

IS - 6

ER -

Addition of lithiated tertiary aromatic amides to epoxides and aziridines: Asymmetric synthesis of (S)-(+)-mellein

Abstract

Keywords

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CCDC 288095: Experimental Crystal Structure Determination

Cite this

Addition of lithiated tertiary aromatic amides to epoxides and aziridines: Asymmetric synthesis of (S)-(+)-mellein

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Datasets

CCDC 288095: Experimental Crystal Structure Determination

Cite this