Abstract
Injuries to peripheral nerves are common and cause life-changing problems for patients alongside high social and health care costs for society. Current clinical treatment of peripheral nerve injuries predominantly relies on sacrificing a section of nerve from elsewhere in the body to provide a graft at the injury site. Much work has been done to develop a bioengineered nerve graft, precluding sacrifice of a functional nerve. Stem cells are prime candidates as accelerators of regeneration in these nerve grafts. This review examines the potential of adipose-derived stem cells to improve nerve repair assisted by bioengineered nerve grafts.
| Original language | Undefined |
|---|---|
| Pages (from-to) | 1341-1346 |
| Number of pages | 6 |
| Journal | Neural Regeneration Research |
| Volume | 9 |
| Issue number | 14 |
| DOIs | |
| Publication status | Published - 15 Jul 2014 |
Keywords
- Adipose derived stem cells
- Axonal regeneration
- Bioengineered nerve graft
- Cell therapy
- Nerve guidance tubes
- Nerve repair
- Peripheral nerve injury
- Schwann cell
Research Beacons, Institutes and Platforms
- Manchester Institute for Collaborative Research on Ageing