TY - BOOK
T1 - Adipose-derived stem cells and nerve regeneration
T2 - Promises and pitfalls
AU - Faroni, A.
AU - Terenghi, G.
AU - Reid, A.J.
PY - 2013
Y1 - 2013
N2 - In order to improve the outcome of nerve regeneration following peripheral trauma injuries, the development of bioengineered nerve grafts has attracted great attention in the field of tissue engineering. Adult stem cells constitute the ideal alternative to Schwann cells (SCs) as transplantable cells in bioartificial nerve grafts. Among the various sources of stem cells with potential applications for regenerative medicine, the adipose tissue has been proven to be one of the most promising. Adipose-derived stem cells (ASCs) are easily obtained, rapidly expanded, show low immunogenicity, and can be differentiated into SCs in vitro. This chapter will focus on recent advances in the use of differentiated and undifferentiated ASCs for peripheral nerve regeneration, with a critical attention for the clinical exploitability of ASC in nerve repair strategies. © 2013 Elsevier Inc.
AB - In order to improve the outcome of nerve regeneration following peripheral trauma injuries, the development of bioengineered nerve grafts has attracted great attention in the field of tissue engineering. Adult stem cells constitute the ideal alternative to Schwann cells (SCs) as transplantable cells in bioartificial nerve grafts. Among the various sources of stem cells with potential applications for regenerative medicine, the adipose tissue has been proven to be one of the most promising. Adipose-derived stem cells (ASCs) are easily obtained, rapidly expanded, show low immunogenicity, and can be differentiated into SCs in vitro. This chapter will focus on recent advances in the use of differentiated and undifferentiated ASCs for peripheral nerve regeneration, with a critical attention for the clinical exploitability of ASC in nerve repair strategies. © 2013 Elsevier Inc.
UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84884692726&partnerID=MN8TOARS
U2 - 10.1016/B978-0-12-410499-0.00005-8
DO - 10.1016/B978-0-12-410499-0.00005-8
M3 - Book
BT - Adipose-derived stem cells and nerve regeneration
ER -