Adipose-derived stem cells: Selecting for translational success.

Kavan S Johal, Adam Reid, Vivien C. Lees

Research output: Contribution to journalArticlepeer-review


We have witnessed a rapid expansion of in vitro characterization and differentiation of adipose-derived stem cells, with increasing translation to both in vivo models and a breadth of clinical specialties. However, an appreciation of the truly heterogeneous nature of this unique stem cell group has identified a need to more accurately delineate subpopulations by any of a host of methods, to include functional properties or surface marker expression. Cells selected for improved proliferative, differentiative, angiogenic or ischemia-resistant properties are but a few attributes that could prove beneficial for targeted treatments or therapies. Optimizing cell culture conditions to permit re-introduction to patients is critical for clinical translation.
Original languageUndefined
Number of pages18
JournalRegenerative Medicine
Issue number1
Publication statusPublished - 1 Jan 2015

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