Adiposity and cancer risk: new mechanistic insights from epidemiology

A G Renehan; M Zwahlen; M Egger

doi:10.1038/nrc3967

Adiposity and cancer risk: new mechanistic insights from epidemiology

A G Renehan, M Zwahlen, M Egger

Research output: Contribution to journal › Article › peer-review

Abstract

Excess body adiposity, commonly expressed as body mass index (BMI), is a risk factor for many common adult cancers. Over the past decade, epidemiological data have shown that adiposity-cancer risk associations are specific for gender, site, geographical population, histological subtype and molecular phenotype. The biological mechanisms underpinning these associations are incompletely understood but need to take account of the specificities observed in epidemiology to better inform future prevention strategies.

Original language	English
Pages (from-to)	484-98
Number of pages	385
Journal	Nat Rev Cancer
Volume	15
Issue number	8
DOIs	https://doi.org/10.1038/nrc3967
Publication status	Published - 2015

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10.1038/nrc3967

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Cite this

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abstract = "Excess body adiposity, commonly expressed as body mass index (BMI), is a risk factor for many common adult cancers. Over the past decade, epidemiological data have shown that adiposity-cancer risk associations are specific for gender, site, geographical population, histological subtype and molecular phenotype. The biological mechanisms underpinning these associations are incompletely understood but need to take account of the specificities observed in epidemiology to better inform future prevention strategies.",

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AU - Zwahlen, M

AU - Egger, M

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AB - Excess body adiposity, commonly expressed as body mass index (BMI), is a risk factor for many common adult cancers. Over the past decade, epidemiological data have shown that adiposity-cancer risk associations are specific for gender, site, geographical population, histological subtype and molecular phenotype. The biological mechanisms underpinning these associations are incompletely understood but need to take account of the specificities observed in epidemiology to better inform future prevention strategies.

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JO - Nat Rev Cancer

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ER -

Adiposity and cancer risk: new mechanistic insights from epidemiology

Abstract

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