Adsorption of bovine serum albumin (BSA) on clinoptilolite

Murat Akgul, Nese Savak, Meryem Ozmak, Ahu Gumrah Dumanli, Yuda Yurum, Abdulkerim Karabakan

Research output: Contribution to journalArticlepeer-review

Abstract

The purpose of the present work was to investigate the adsorption of BSA on clinoptilolite in aqueous media. In this
study, batch adsorption experiments were carried out and the effects of pH, protein concentration, ionic strength and
modification of zeolite on the adsorption process were examined. The optimum pH for adsorption was found to be
4.0. It was found that various treatments applied to modify clinoptilolite has a substantial effect on the adsorption. In
adsorption studies, residual BSA concentration reached equilibrium in a short duration of 60 min. Maximum
adsorption capacity value for clinoptilolite in the original form is 388.3 mg BSA/g zeolite (23.2 mg BSA/m2) and in the
modified form ranges from 500-660 mg BSA/g zeolite (25-33 mg BSA/m2) showed that this adsorbent, clinoptilolite,
was suitable for the adsorption of BSA from aqueous media.
Original languageEnglish
Pages (from-to)21-29
Number of pages9
JournalHacettepe Journal of Biology and Chemistry
Volume36
Issue number1
Publication statusPublished - 2008

Keywords

  • Clinoptilolite
  • bovine serum albumin
  • absorption

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