Adult stem cells in tissue engineering

Thomas Hodgkinson, Xue Feng Yuan, Ardeshir Bayat

    Research output: Contribution to journalArticlepeer-review


    Tissue engineering is a rapidly evolving field of research that has yet to fulfil its promise in the translation and potential application of adult stem cells in clinical practice. Recently, it has become apparent that specific adult stem cells are capable of transdifferentiation. The successful application of adult stem cells is thought to be central in creating truly biomimetic tissue. Although still most widely utilized, research suggests that in the future, bone marrow-derived stem cells may no longer be considered the most suitable candidates for use in tissue engineering. Independent studies have successfully engineered a range of tissues in vitro and in vivo using hair follicle- and adipose-derived stem cells. Owing to their potency, relative abundance and noninvasive extraction, these populations may be the most promising studied to date. This review aims to discuss these candidate adult stem cell populations in an attempt to assess the most promising avenues of research. © 2009 Expert Reviews Ltd.
    Original languageEnglish
    Pages (from-to)621-640
    Number of pages19
    JournalExpert Review of Medical Devices
    Issue number6
    Publication statusPublished - Dec 2009


    • Adipose
    • Adult stem cell
    • Bone marrow
    • Bulge
    • Hair follicle
    • Hematopoietic
    • Mesenchymal
    • Neural
    • Tissue engineering


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