Advances in stem cell research and therapeutic development

Michele De Luca, Alessandro Aiuti, Giulio Cossu, Malin Parmar, Graziella Pellegrini, Pamela Gehron Robey

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Despite many reports of putative stem-cell-based treatments in genetic and degenerative disorders or severe injuries, the number of proven stem cell therapies has remained small. In this Review, we survey advances in stem cell research and describe the cell types that are currently being used in the clinic or are close to clinical trials. Finally, we analyse the scientific rationale, experimental approaches, caveats and results underpinning the clinical use of such stem cells.

Original languageEnglish
Pages (from-to)801-811
Number of pages11
JournalNature Cell Biology
Issue number7
Early online date17 Jun 2019
Publication statusPublished - 1 Jul 2019


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