Air- and water-stable Lewis acids: Synthesis and reactivity of P-trifluoromethyl electrophilic phosphonium cations

V. Fasano, J. H.W. LaFortune, J. M. Bayne, M. J. Ingleson, D. W. Stephan

    Research output: Contribution to journalArticlepeer-review

    Abstract

    A new class of electrophilic phosphonium cations (EPCs) containing a -CF3 group attached to the phosphorus(v) center is readily accessible in high yields, via a scalable process. These species are stable to air, water, alcohol and strong Brønsted acid, even at raised temperatures. Thus, P-CF3 EPCs are more robust than previously reported EPCs containing P-X moieties (X = F, Cl, OR), and despite their reduced Lewis acidity they function as Lewis acid catalysts without requiring anhydrous reaction conditions.

    Original languageEnglish
    Pages (from-to)662-665
    Number of pages4
    JournalChemical Communications
    Volume54
    Issue number6
    Early online date21 Dec 2017
    DOIs
    Publication statusPublished - 2018

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