Abstract
There is an ever-increasing understanding of the mechanisms by which pathogens such as bacteria, viruses, and protozoa activate dendritic cells (DCs) to drive T helper type 1 (Th1) responses, but we know much less about how these cells elicit Th2 responses. This gap in our knowledge puts us at a distinct disadvantage in designing therapeutics for certain immune-mediated diseases. However, progress is being made with the identification of novel endogenous tissue factors that can enhance Th2 induction by DCs. JEM © The Rockefeller University Press.
| Original language | English |
|---|---|
| Pages (from-to) | 13-17 |
| Number of pages | 4 |
| Journal | Journal of Experimental Medicine |
| Volume | 205 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 21 Jan 2008 |