Allergic and Noninvasive Infectious Pulmonary Aspergillosis Syndromes

Eavan G. Muldoon, Mary E. Strek, Karen C. Patterson

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Aspergillus spp are ubiquitous in the environment and inhalation of Aspergillus spores is unavoidable. An intact immune system, with normal airway function, protects most people from disease. Globally however, the toll from aspergillosis is high. The literature has largely focused on invasive aspergillosis, yet the burden in terms of chronicity and prevalence is higher for noninvasive Aspergillus conditions. This review discusses allergic aspergilloses; an update on diagnosis and management of allergic bronchopulmonary aspergillosis, including in patients with cystic fibrosis, and an update on severe asthma with fungal sensitization. Additionally, the presentation, investigation and management of noninvasive infectious aspergilloses are reviewed.

Original languageEnglish
JournalClinics in Chest Medicine
Early online date12 Jun 2017
Publication statusPublished - 2017


  • ABPA
  • Aspergillus
  • Aspergillus bronchitis
  • Chronic fungal infection of lung


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