TY - JOUR
T1 - Allergic and Noninvasive Infectious Pulmonary Aspergillosis Syndromes
AU - Muldoon, Eavan G.
AU - Strek, Mary E.
AU - Patterson, Karen C.
PY - 2017
Y1 - 2017
N2 - Aspergillus spp are ubiquitous in the environment and inhalation of Aspergillus spores is unavoidable. An intact immune system, with normal airway function, protects most people from disease. Globally however, the toll from aspergillosis is high. The literature has largely focused on invasive aspergillosis, yet the burden in terms of chronicity and prevalence is higher for noninvasive Aspergillus conditions. This review discusses allergic aspergilloses; an update on diagnosis and management of allergic bronchopulmonary aspergillosis, including in patients with cystic fibrosis, and an update on severe asthma with fungal sensitization. Additionally, the presentation, investigation and management of noninvasive infectious aspergilloses are reviewed.
AB - Aspergillus spp are ubiquitous in the environment and inhalation of Aspergillus spores is unavoidable. An intact immune system, with normal airway function, protects most people from disease. Globally however, the toll from aspergillosis is high. The literature has largely focused on invasive aspergillosis, yet the burden in terms of chronicity and prevalence is higher for noninvasive Aspergillus conditions. This review discusses allergic aspergilloses; an update on diagnosis and management of allergic bronchopulmonary aspergillosis, including in patients with cystic fibrosis, and an update on severe asthma with fungal sensitization. Additionally, the presentation, investigation and management of noninvasive infectious aspergilloses are reviewed.
KW - ABPA
KW - Aspergillus
KW - Aspergillus bronchitis
KW - Chronic fungal infection of lung
UR - http://www.scopus.com/inward/record.url?scp=85020423106&partnerID=8YFLogxK
U2 - 10.1016/j.ccm.2017.04.012
DO - 10.1016/j.ccm.2017.04.012
M3 - Article
AN - SCOPUS:85020423106
JO - Clinics in Chest Medicine
JF - Clinics in Chest Medicine
SN - 0272-5231
ER -