Abstract
The site opposite an end-to-side anastomosis, resulting from femoral bypass surgery, and the carotid sinus are two regions well known to be prone to fibrous intimal hyperplasia or atherogenesis, respectively. The blood flow at these two sites features a stagnation point, which oscillates in strength and position. Mathematical models are used to determine some of the features of such a flow; in particular, the mean wall shear stress is calculated. The positional oscillations cause a significant change in the distribution and magnitude of the mean wall shear stress from that of the well studied case of a stagnation point that oscillates only in strength. It is therefore proposed that the recorded effect of time dependence in the flow upon atherogenesis could still be a result of the distribution of the mean and not the time- varying components of the wall shear stress.
| Original language | English |
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| Pages (from-to) | 227-237 |
| Number of pages | 10 |
| Journal | Journal of Biomechanical Engineering |
| Volume | 120 |
| Issue number | 2 |
| Publication status | Published - Apr 1998 |