An analysis of the metabolic syndrome phenotype in systemic lupus erythematosus

B. Parker; Y. Ahmad; J. Shelmerdine; H. Edlin; A. P. Yates; L. S. Teh; I. N. Bruce

doi:10.1177/0961203311416695

An analysis of the metabolic syndrome phenotype in systemic lupus erythematosus

B. Parker, Y. Ahmad, J. Shelmerdine, H. Edlin, A. P. Yates, L. S. Teh, I. N. Bruce

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Abstract

Systemic lupus erythematosus (SLE) is associated with an increased risk of coronary heart disease (CHD) not fully explained by classic risk factors. Metabolic syndrome (MetS) is associated with an increased risk of CHD in the general population and whilst its prevalence is increased in SLE, its phenotypic expression may differ. We studied 200 women with SLE and 100 controls and compared the prevalence of MetS and its individual components. We examined whether any SLE features were associated with MetS and whether MetS in SLE patients was associated with carotid plaque. Patients with SLE were more likely to meet the MetS criteria (age-adjusted OR 2.1 (1.1-3.8)). However, this was not due to increased central obesity (median waist circumference 84 cm vs. 82 cm, p = 0.65) but rather increased prevalence of hypertension (p

Original language	English
Pages (from-to)	1459-1465
Number of pages	6
Journal	Lupus
Volume	20
Issue number	14
DOIs	https://doi.org/10.1177/0961203311416695
Publication status	Published - Dec 2011

Keywords

atherosclerosis
metabolic syndrome
systemic lupus erythematosus

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Cite this

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AU - Parker, B.

AU - Ahmad, Y.

AU - Shelmerdine, J.

AU - Edlin, H.

AU - Yates, A. P.

AU - Teh, L. S.

AU - Bruce, I. N.

PY - 2011/12

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An analysis of the metabolic syndrome phenotype in systemic lupus erythematosus

Abstract

Keywords

UN SDGs

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