An automated cocktail method for in vitro assessment of direct and time-dependent inhibition of nine major cytochrome P450 enzymes-application to establishing CYP2C8 inhibitor selectivity

Helina Kahma; Laura Aurinsalo; Mikko Neuvonen; Jani Katajamaki; Marie-Noelle Paludetto; Jenni Viinamaki; Terhi Launiainen; Anne M. Filppula; Aleksi Tornio; Mikko Niemi; Janne T. Backman

doi:10.1016/J.EJPS.2021.105810

An automated cocktail method for in vitro assessment of direct and time-dependent inhibition of nine major cytochrome P450 enzymes-application to establishing CYP2C8 inhibitor selectivity

Helina Kahma, Laura Aurinsalo, Mikko Neuvonen, Jani Katajamaki, Marie-Noelle Paludetto, Jenni Viinamaki, Terhi Launiainen, Anne M. Filppula, Aleksi Tornio, Mikko Niemi, Janne T. Backman

Pharmacy

Research output: Contribution to journal › Article › peer-review

Original language	Undefined
Journal	European Journal of Pharmaceutical Sciences
DOIs	https://doi.org/10.1016/J.EJPS.2021.105810
Publication status	Published - 2021

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10.1016/J.EJPS.2021.105810

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Kahma, H., Aurinsalo, L., Neuvonen, M., Katajamaki, J., Paludetto, M.-N., Viinamaki, J., Launiainen, T., Filppula, A. M., Tornio, A., Niemi, M., & Backman, J. T. (2021). An automated cocktail method for in vitro assessment of direct and time-dependent inhibition of nine major cytochrome P450 enzymes-application to establishing CYP2C8 inhibitor selectivity. European Journal of Pharmaceutical Sciences. https://doi.org/10.1016/J.EJPS.2021.105810

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title = "An automated cocktail method for in vitro assessment of direct and time-dependent inhibition of nine major cytochrome P450 enzymes-application to establishing CYP2C8 inhibitor selectivity",

author = "Helina Kahma and Laura Aurinsalo and Mikko Neuvonen and Jani Katajamaki and Marie-Noelle Paludetto and Jenni Viinamaki and Terhi Launiainen and Filppula, {Anne M.} and Aleksi Tornio and Mikko Niemi and Backman, {Janne T.}",

year = "2021",

doi = "10.1016/J.EJPS.2021.105810",

language = "Undefined",

journal = "European Journal of Pharmaceutical Sciences",

issn = "0928-0987",

publisher = "Elsevier BV",

}

Kahma, H, Aurinsalo, L, Neuvonen, M, Katajamaki, J, Paludetto, M-N, Viinamaki, J, Launiainen, T, Filppula, AM, Tornio, A, Niemi, M & Backman, JT 2021, 'An automated cocktail method for in vitro assessment of direct and time-dependent inhibition of nine major cytochrome P450 enzymes-application to establishing CYP2C8 inhibitor selectivity', European Journal of Pharmaceutical Sciences. https://doi.org/10.1016/J.EJPS.2021.105810

TY - JOUR

T1 - An automated cocktail method for in vitro assessment of direct and time-dependent inhibition of nine major cytochrome P450 enzymes-application to establishing CYP2C8 inhibitor selectivity

AU - Kahma, Helina

AU - Aurinsalo, Laura

AU - Neuvonen, Mikko

AU - Katajamaki, Jani

AU - Paludetto, Marie-Noelle

AU - Viinamaki, Jenni

AU - Launiainen, Terhi

AU - Filppula, Anne M.

AU - Tornio, Aleksi

AU - Niemi, Mikko

AU - Backman, Janne T.

PY - 2021

Y1 - 2021

UR - https://publons.com/wos-op/publon/46124879/

U2 - 10.1016/J.EJPS.2021.105810

DO - 10.1016/J.EJPS.2021.105810

M3 - Article

SN - 0928-0987

JO - European Journal of Pharmaceutical Sciences

JF - European Journal of Pharmaceutical Sciences

ER -

An automated cocktail method for in vitro assessment of direct and time-dependent inhibition of nine major cytochrome P450 enzymes-application to establishing CYP2C8 inhibitor selectivity

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